Evidence map›Paper›PMID 31598134›Full record

ArticleTherapeutic advances in gastroenterology2019

Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China.

Ling-Zhi Yuan, Ping Yi, Gang-Shi Wang, Shi-Yun Tan, Guang-Ming Huang, Ling-Zhi Qi, Yan Jia, Fen Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  12. Analysis of Risk Factors and Circumferential Distribution of Exposed Cardiac Glands.JGH open : an open access journal of gastroenterology and hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Ling-Zhi YuanDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0001-5004-494X
Ping YiDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Gang-Shi WangDepartment of Gastroenterology, The General Hospital of Chinese People's Liberation Army, Beijing, China.
Shi-Yun TanDepartment of Gastroenterology, The People's Hospital of Wuhan University, Hubei, China.
Guang-Ming HuangDepartment of Gastroenterology, The Second Affiliated Hospital of Nanjing Medical University, Jiangsu, China.
Ling-Zhi QiDepartment of Gastroenterology, The People's Hospital of Jilin Province, Changchun, China.
Yan JiaDepartment of Gastroenterology, Army General Hospital, Beijing, China.
Fen WangDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Road, Changsha 410013, Hunan, China.
Central South University · CNChinese General Hospital College of Nursing and Liberal Arts · PHPeople 's Hospital of Jilin Province · CNSecond Affiliated Hospital of Nanjing Medical University · CNThe Military General Hospital of Beijing PLA · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor habits can worsen gastroesophageal reflux disease (GERD) and reduce treatment efficacy. Few large-scale studies have examined lifestyle influences, particularly eating habits, on GERD in China, and research related to eating quickly, hyperphagia, and eating hot foods is quite limited. The aim of this study was to evaluate the relationship between GERD pathogenesis and lifestyle factors to produce useful information for the development of a clinical reference guide through a national multicenter survey in China.

methodsSymptom and lifestyle/habit questionnaires included 19 items were designed. The questionnaire results were subjected to correlation analysis relative to GERD symptom onset. A standard proton pump inhibitor (PPI) was advised to correct patients with unhealthful lifestyle habits.

resultsA total of 1518 subjects (832 GERD, 686 non-GERD) enrolled from six Chinese hospitals completed symptom and lifestyle/habit questionnaires. The top lifestyle factors related to GERD were fast eating, eating beyond fullness, and preference for spicy food. Univariate analysis showed that 21 factors, including male gender, a supra-normal body mass index (BMI), smoking, drinking alcohol, fast eating, eating beyond fullness, eating very hot foods, and drinking soup, among others, were associated with GERD (

conclusionsLifestyle interventions can improve medication efficacy in GERD patients. Numerous habits, including fast eating, eating beyond fullness, and eating very hot foods, were associated with GERD pathogenesis. The present results may be useful as a reference for preventive education and treatment.

Indexed as

dietary habitsgastroesophageal reflux disease (GERD)hyperphagialife styletherapeutics

Identifiers

PMID31598134
PMCPMC6764031
OpenAlexW2975626644

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.