Evidence map›Paper›PMID 31597780›Full record

ArticleJournal of virology2019

Interviral Recombination between Plant, Insect, and Fungal RNA Viruses: Role of the Intracellular Ca

Nikolay Kovalev, Judit Pogany, Peter D Nagy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nikolay KovalevDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
Judit PoganyDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
Peter D NagyDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA pdnagy2@uky.edu.
University of Kentucky · US

Funding

Blocking RNA virus replication through the antiviral functions of cellular helicasesR21AI122078 · NIAID · UNIVERSITY OF KENTUCKY · PI NAGY, PETER · 2016 to 2017
$385k
NIAID NIH HHS R21 AI122078
6 · The paper itself

Abstract

Recombination is one of the driving forces of viral evolution. RNA recombination events among similar RNA viruses are frequent, although RNA recombination could also take place among unrelated viruses. In this paper, we have established efficient interviral recombination systems based on yeast and plants. We show that diverse RNA viruses, including the plant viruses tomato bushy stunt virus, carnation Italian ringspot virus, and turnip crinkle virus-associated RNA; the insect plus-strand RNA [(+)RNA] viruses Flock House virus and Nodamura virus; and the double-stranded L-A virus of yeast, are involved in interviral recombination events. Most interviral recombinants are minus-strand recombinant RNAs, and the junction sites are not randomly distributed, but there are certain hot spot regions. Formation of interviral recombinants in yeast and plants is accelerated by depletion of the cellular SERCA-like Pmr1 ATPase-driven Ca

Indexed as

Agrobacterium tumefaciensCalciumCalcium-Transporting ATPasesCarmovirusCations, DivalentCell-Free SystemIon TransportManganeseMolecular ChaperonesNicotianaNodaviridaeRecombination, GeneticRNA-Dependent RNA PolymeraseRNA, ViralSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCalciumCalcium-Transporting ATPasesCations, DivalentManganeseMolecular ChaperonesRNA-Dependent RNA PolymeraseRNA, ViralSaccharomyces cerevisiae ProteinsSSC1 protein, S cerevisiaeViral Proteinscalcium manganese pumphost factorinterviralplantreplicase complexreplicationRNA recombinationTBSVtombusvirusyeast

Identifiers

PMID31597780
PMCPMC6912095
OpenAlexW2979496291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.