Evidence map›Paper›PMID 31597773›Full record

ArticleJournal of virology2019

Yellow Fever Virus Reemergence and Spread in Southeast Brazil, 2016-2019.

Marta Giovanetti, Marcos Cesar Lima de Mendonça, Vagner Fonseca, Maria Angélica Mares-Guia, Allison Fabri, Joilson Xavier, Jaqueline Goes de Jesus, Tiago Gräf, Cintia Damasceno Dos Santos Rodrigues, Carolina Cardoso Dos Santos and 19 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Distribution of yellow fever vectors in a disease-free area of Northeast Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Article
  7. Review
  8. Article
  9. Article
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  13. Perspective of Quilombola Communities in Brazil on a Yellow Fever Outbreak and Vaccination.The American journal of tropical medicine and hygiene · 2025
    Article
  14. Review
  15. Article
  16. Article
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  19. Article
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Marta Giovanetti *Laboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil giovanetti.marta@gmail.com.ORCID 0000-0002-5849-7326
Marcos Cesar Lima de Mendonça *Laboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Vagner FonsecaLaboratório de Genética Celular e Molecular, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Maria Angélica Mares-GuiaLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Allison FabriLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Joilson XavierLaboratório de Genética Celular e Molecular, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Jaqueline Goes de JesusInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Bahia, Brazil.
Tiago GräfInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Bahia, Brazil.
Cintia Damasceno Dos Santos RodriguesLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Carolina Cardoso Dos SantosLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Simone Alves SampaioLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Flavia Lowen Levy ChalhoubLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Fernanda de Bruycker NogueiraLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Julien ThezeDepartment of Zoology, University of Oxford, Oxford, United Kingdom.
Alessandro Pecego Martins RomanoCoordenação Geral de Vigilância de Arboviroses (CGARB), Ministério da Saúde, (CGLAB/SVS-MS), Brasília, Brazil.
Daniel Garkauskas RamosCoordenação Geral de Vigilância de Arboviroses (CGARB), Ministério da Saúde, (CGLAB/SVS-MS), Brasília, Brazil.
Andre Luiz de AbreuCoordenação Geral dos Laboratórios de Saúde Pública/Secretaria de Vigilância em Saúde, Ministério da Saúde, (CGLAB/SVS-MS), Brasília, Brazil.
Wanderson Kleber OliveiraSecretaria de Vigilância em Saúde, Ministério da Saúde (SVS-MS), Brasília, Brazil.
Rodrigo Fabiano do Carmo SaidCoordenação Geral de Vigilância de Arboviroses (CGARB), Ministério da Saúde, (CGLAB/SVS-MS), Brasília, Brazil.
Carlos F Campelo de AlburqueOrganização Pan-Americana da Saúde/Organização Mundial da Saúde, Brasília, Brazil.
Tulio de OliveiraKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Carlos Augusto FernandesLaboratório Central de Saúde Pública Noel Nutels (LACEN-RJ), Rio de Janeiro, Brazil.
Shirlei Ferreira AguiarLaboratório Central de Saúde Pública Noel Nutels (LACEN-RJ), Rio de Janeiro, Brazil.
Alexandre ChieppeSuperintendência de Vigilância do Estado, Rio de Janeiro, Brazil.
Patrícia Carvalho SequeiraLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Nuno Rodrigues FariaDepartment of Zoology, University of Oxford, Oxford, United Kingdom.
Rivaldo Venâncio CunhaFundação Oswaldo Cruz, Bio-Manguinhos, Rio de Janeiro, Brazil.
Luiz Carlos Junior AlcantaraLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.
Ana Maria Bispo de FilippisLaboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent reemergence of yellow fever virus (YFV) in Brazil has raised serious concerns due to the rapid dissemination of the virus in the southeastern region. To better understand YFV genetic diversity and dynamics during the recent outbreak in southeastern Brazil, we generated 18 complete and nearly complete genomes from the peak of the epidemic curve from nonhuman primates (NHPs) and human infected cases across the Espírito Santo and Rio de Janeiro states. Genomic sequencing of 18 YFV genomes revealed the estimated timing, source, and likely routes of yellow fever virus transmission and dispersion during one of the largest outbreaks ever registered in Brazil. We showed that during the recent epidemic, YFV was reintroduced from Minas Gerais to the Espírito Santo and Rio de Janeiro states multiple times between 2016 and 2019. The analysis of data from portable sequencing could identify the corridor of spread of YFV. These findings reinforce the idea that continued genomic surveillance strategies can provide information on virus genetic diversity and transmission dynamics that might assist in understanding arbovirus epidemics.

Indexed as

Disease OutbreaksGenome, ViralAedesAlouattaAnimalsBrazilCallithrixCebusFemaleGenetic VariationHumansIncidenceLeontopithecusMaleMosquito VectorsPhylogenygenomic surveillanceoutbreakoutbreak responseSoutheast Brazilyellow fever

Identifiers

PMID31597773
PMCPMC6912119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.