Evidence map›Paper›PMID 31597764›Full record

ArticleJournal of virology2019

Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy.

Marta Massanella, Wendy Bakeman, Pasiri Sithinamsuwan, James L K Fletcher, Nitiya Chomchey, Somporn Tipsuk, Thep Chalermchai, Jean-Pierre Routy, Jintanat Ananworanich, Victor G Valcour and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. EcoHIV Infection Promotes Atherosclerosis Progression in LDLR-Deficient Mice.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
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  7. Review
  8. Article
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  12. Virologie (Montrouge, France) · 2022
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  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Marta MassanellaCentre de Recherche du CHUM, Montréal, Québec, Canada.ORCID 0000-0002-3326-151X
Wendy BakemanVGTI-Florida, Port St. Lucie, Florida, USA.
Pasiri SithinamsuwanPhramongkutklao Hospital, Bangkok, Thailand.
James L K FletcherSEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Nitiya ChomcheySEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Somporn TipsukSEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Thep ChalermchaiSEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Jean-Pierre RoutyChronic Viral Illness Service and Division of Hematology, Research Institute, McGill University Health Centre, Montréal, Québec, Canada.
Jintanat AnanworanichSEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Victor G ValcourDepartment of Neurology, University of California, San Francisco, San Francisco, California, USA.
Nicolas ChomontCentre de Recherche du CHUM, Montréal, Québec, Canada nicolas.chomont@umontreal.ca.ORCID 0000-0001-9747-5018
Thai Red Cross Society · THCentre Hospitalier de l’Université de Montréal · CAHenry M. Jackson Foundation · USMcGill University Health Centre · CAPhramongkutklao Hospital · THUniversity of California, San Francisco · USVaccine & Gene Therapy Institute of Florida · US

Funding

Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIVR01NS061696 · NINDS · UNIVERSITY OF HAWAII AT MANOA · PI VALCOUR, VICTOR · 2008 to 2012
$3.2M
CIHR 364408CIHR HIG-133050NINDS NIH HHS R01 NS061696
6 · The paper itself

Abstract

Whereas human immunodeficiency virus (HIV) persists in tissue macrophages during antiretroviral therapy (ART), the role of circulating monocytes as HIV reservoirs remains controversial. Three magnetic bead selection methods and flow cytometry cell sorting were compared for their capacity to yield pure CD14

Indexed as

Anti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountCD4-Positive T-LymphocytesCohort StudiesDNA, ViralFlow CytometryHIV-1HIV InfectionsHumansImmunophenotypingMaleMiddle AgedMonocytesPrimary Cell CultureThailandAnti-HIV AgentsDNA, ViralHIV reservoirintegrated HIV DNAmonocytes

Identifiers

PMID31597764
PMCPMC6912110
OpenAlexW2979782115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.