Evidence map›Paper›PMID 31597721›Full record

ArticlemSphere2019

A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent Oncogene.

Andelé M Conradie, Luca D Bertzbach, Nirajan Bhandari, Mark Parcells, Benedikt B Kaufer

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andelé M ConradieInstitut für Virologie, Freie Universität Berlin, Berlin, Germany.ORCID 0000-0001-9975-0642
Luca D BertzbachInstitut für Virologie, Freie Universität Berlin, Berlin, Germany.ORCID 0000-0002-0698-5395
Nirajan BhandariDepartment of Animal and Food Sciences, University of Delaware, Newark, Delaware, USA.
Mark ParcellsDepartment of Animal and Food Sciences, University of Delaware, Newark, Delaware, USA.
Benedikt B KauferInstitut für Virologie, Freie Universität Berlin, Berlin, Germany b.kaufer@fu-berlin.de.ORCID 0000-0003-1328-2695
Freie Universität Berlin · DEUniversity of Delaware · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed against the highly oncogenic herpesvirus Marek's disease virus (MDV). MDV infects chickens and causes severe immunosuppression, neurological signs, and fatal lymphomas, a process that requires the viral oncogene,

Indexed as

AnimalsChickensHerpesvirus 2, GallidMarek DiseaseMarek Disease VaccinesOncogene Proteins, ViralVaccines, AttenuatedVaccines, SyntheticEco-Q protein, Gallid herpesvirus 2Marek Disease VaccinesOncogene Proteins, ViralVaccines, AttenuatedVaccines, Syntheticbasic leucine zipper (bZIP) proteincancerCVI988/Rispensherpesvirus telomerase RNA (vTR)Marek’s disease virus (MDV)meq geneT cell lymphomatumorigenesisvaccine

Identifiers

PMID31597721
PMCPMC6796977
OpenAlexW2979869287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.