Evidence map›Paper›PMID 31597720›Full record

ArticlemSphere2019

Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii.

Woei C Lam, Rajendra Upadhya, Charles A Specht, Abigail E Ragsdale, Camaron R Hole, Stuart M Levitz, Jennifer K Lodge

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Acetylation and accessibility ofCell surface (Amsterdam, Netherlands) · 2026
    Article
  3. Molecular Architecture ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Immune evasion byFrontiers in immunology · 2024
    Article
  12. Architecture of the dynamic fungal cell wall.Nature reviews. Microbiology · 2023
    Review
  13. Cell wall composition inFrontiers in fungal biology · 2023
    Article
  14. Gene, virulence and related regulatory mechanisms inActa biochimica et biophysica Sinica · 2022
    Review
  15. Article
  16. Cell surface (Amsterdam, Netherlands) · 2021
    Article
  17. Article
  18. Cryptococcus neoformans: Sex, morphogenesis, and virulence.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Woei C LamDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Rajendra UpadhyaDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Charles A SpechtDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Abigail E RagsdaleDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Camaron R HoleDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Stuart M LevitzDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Jennifer K LodgeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA lodgejk@wustl.edu.
Washington University in St. Louis · USUniversity of Massachusetts Chan Medical School · US

Funding

Preclinical studies of a Cryptococcus vaccine for AIDS patientsR01AI125045 · NIAID · WASHINGTON UNIVERSITY · PI LEVITZ, STUART MICHAEL, LODGE, JENNIFER K. · 2016 to 2025
$7.1M
ROLE OF MACROPHAGES IN CRYPTOCOCCAL INFECTIONSR01AI025780 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEVITZ, STUART MICHAEL · 1987 to 2019
$7.1M
Chitosan in CryptococcusR01AI072195 · NIAID · WASHINGTON UNIVERSITY · PI LODGE, JENNIFER K. · 2008 to 2018
$3.5M
NIAID NIH HHS R01 AI025780NIAID NIH HHS R01 AI072195NIAID NIH HHS R01 AI125045
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmidohydrolasesAnimalsCell WallChitosanCryptococcosisCryptococcus gattiiFemaleFungal ProteinsGene DeletionGene Expression Regulation, FungalHumansMiceMice, Inbred C57BLMice, Inbred CBAVirulenceVirulence FactorsAmidohydrolaseschitin deacetylaseChitosanFungal ProteinsVirulence Factorschitinchitosanchitosan regulationCryptococcus gattiiprotectionR265vaccinevirulence

Identifiers

PMID31597720
PMCPMC6796976
OpenAlexW2979378522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.