Evidence map›Paper›PMID 31597719›Full record

ArticlemSphere2019

Alteration of Prion Strain Emergence by Nonhost Factors.

Sara A M Holec, Qi Yuan, Jason C Bartz

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Chronic Wasting Disease: State of the Science.Pathogens (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. The role of prion strain diversity in the development of successful therapeutic treatments.Progress in molecular biology and translational science · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara A M HolecDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Qi YuanDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Jason C BartzDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA jbartz@creighton.edu.
Creighton University · US

Funding

Zoonotic potential of CWD and influence of environmental contamination on prion propagationP01AI077774 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI EDWARD Arthur HOOVER · 2008 to 2026
$36.1M
NIAID NIH HHS P01 AI077774
6 · The paper itself

Abstract

Prions can persist in the environment for extended periods of time after adsorption to surfaces, including soils, feeding troughs, or fences. Prion strain- and soil-specific differences in prion adsorption, infectivity, and response to inactivation may be involved in strain maintenance or emergence of new strains in a population. Extensive proteinase K (PK) digestion of Hyper (HY) and Drowsy (DY) PrP

Indexed as

EnvironmentAdsorptionAnimalsCricetinaePrion DiseasesPrionsSoilSpecies SpecificitySurface PropertiesPrionsSoilprionstrainstrain emergence

Identifiers

PMID31597719
PMCPMC6796975
OpenAlexW2979902713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.