ArticlePsychological medicine2020
Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders.
Article in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Association of resting-state EEG with suicidality in depressed patients: a systematic review.BMC psychiatry · 2025Pooled it
- Pooled it
- Brain Functional Network Alterations in Adolescents With Major Depressive Disorder and Suicidal Attempt: A Resting-State fMRI Study.Alpha psychiatry · 2026Article
- Neurophysiological Markers of Regulation Success in Everyday Life in Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Integrating dynamic psychophysiological indices across time and contexts: Elucidating mechanisms, risk markers, and intervention targets.Psychophysiology · 2024Review
- The neural connectome of suicidality in adults with mood and anxiety disorders.Nature. Mental health · 2024Article
- Neuroimaging studies in major depressive disorder with suicidal ideation or behaviour among Chinese patients: implications for neural mechanisms and imaging signatures.General psychiatry · 2024Review
- Connectomics-based resting-state functional network alterations predict suicidality in major depressive disorder.Translational psychiatry · 2023Article
- Negative association between non-suicidal self-injury in adolescents and default mode network activation during the distraction blocks of a rumination task.Suicide & life-threatening behavior · 2023Article
- Reduced suicidality after electroconvulsive therapy is linked to increased frontal brain activity in depressed patients: a resting-state fMRI study.Frontiers in psychiatry · 2023Article
- Neuroimaging alterations of the suicidal brain and its relevance to practice: an updated review of MRI studies.Frontiers in psychiatry · 2023Review
- From Low-Grade Inflammation in Osteoarthritis to Neuropsychiatric Sequelae: A Narrative Review.International journal of molecular sciences · 2022Review
- Spontaneous transient states of fronto-temporal and default-mode networks altered by suicide attempt in major depressive disorder.European archives of psychiatry and clinical neuroscience · 2022Article
- Aberrant resting-state functional connectivity of major depressive disorder with higher risk of suicide.PCN reports : psychiatry and clinical neurosciences · 2022Article
- Altered functional connectivity in first-episode and recurrent depression: A resting-state functional magnetic resonance imaging study.Frontiers in neurology · 2022Article
- Using Network Parcels and Resting-State Networks to Estimate Correlates of Mood Disorder and Related Research Domain Criteria Constructs of Reward Responsiveness and Inhibitory Control.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Translating Interventional Neuroscience to Suicide: It's About Time.Biological psychiatry · 2021Review
- Functional network alterations differently associated with suicidal ideas and acts in depressed patients: an indirect support to the transition model.Translational psychiatry · 2021Article
- New Methods for Assessing Rapid Changes in Suicide Risk.Frontiers in psychiatry · 2021Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundLittle is known about the neural substrates of suicide risk in mood disorders. Improving the identification of biomarkers of suicide risk, as indicated by a history of suicide-related behavior (SB), could lead to more targeted treatments to reduce risk.
methodsParticipants were 18 young adults with a mood disorder with a history of SB (as indicated by endorsing a past suicide attempt), 60 with a mood disorder with a history of suicidal ideation (SI) but not SB, 52 with a mood disorder with no history of SI or SB (MD), and 82 healthy comparison participants (HC). Resting-state functional connectivity within and between intrinsic neural networks, including cognitive control network (CCN), salience and emotion network (SEN), and default mode network (DMN), was compared between groups.
resultsSeveral fronto-parietal regions (k > 57, p < 0.005) were identified in which individuals with SB demonstrated distinct patterns of connectivity within (in the CCN) and across networks (CCN-SEN and CCN-DMN). Connectivity with some of these same regions also distinguished the SB group when participants were re-scanned after 1-4 months. Extracted data defined SB group membership with good accuracy, sensitivity, and specificity (79-88%).
conclusionsThese results suggest that individuals with a history of SB in the context of mood disorders may show reliably distinct patterns of intrinsic network connectivity, even when compared to those with mood disorders without SB. Resting-state fMRI is a promising tool for identifying subtypes of patients with mood disorders who may be at risk for suicidal behavior.
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