SynthesisBiological research for nursing2020
Influence of Maternal Prepregnancy Obesity and Excessive Gestational Weight Gain on Maternal and Child Gastrointestinal Microbiome Composition: A Systematic Review.
Synthesis in Biological research for nursing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- The effect of gestational weight gain on the infant gut microbiome- a systematic review of the literature.Frontiers in cellular and infection microbiology · 2026Pooled it
- The effect of motivational interviewing and/or cognitive behaviour therapy techniques on gestational weight gain - a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Microbiome, Epigenetics, and Nutritional Factors in Shaping Perinatal Pregnancy Outcomes.International journal of molecular sciences · 2026Review
- Dietary pulse prebiotic fibre intake in a rat obese pregnancy model alters maternal caecal microbiome and protects against steatosis in newly weaned offspring.Journal of nutritional science · 2026Article
- Gut Health for Two: the Critical Role of Probiotics and Prebiotics in Pregnancy and Lactation.Current nutrition reports · 2025Review
- Perinatal depressive and anxiety symptoms are associated with gut microbiota in pregnant women with overweight and obesity.Brain, behavior, & immunity - health · 2025Article
- Alterations in Gut Microbiota of Infants Born to Mothers with Obesity.Biomedicines · 2025Article
- Dietary Pea Fibre Improves Obesity, Intestinal Barrier, Reproductive Performance, Offspring Health of Parent Mice Deprived of Dietary Fibre.Animals : an open access journal from MDPI · 2025Article
- Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy - a pilot study.Frontiers in cellular and infection microbiology · 2025Article
- Association between maternal body mass index and hospital admissions for infection in offspring: longitudinal cohort study.BMJ medicine · 2025Article
- Characterization of newborn gut microbiota according to the pre-gestational maternal nutritional status and delivery mode.Archives of gynecology and obstetrics · 2024Article
- Influence of Early Life Factors on the Breast Milk and Fecal Microbiota of Mother-Newborn Dyads.Microorganisms · 2024Article
- Host-gut microbiota interactions during pregnancy.Evolution, medicine, and public health · 2024Review
- Pre-pregnancy body mass index and gut microbiota of mothers and children 5 years postpartum.International journal of obesity (2005) · 2023Article
- Composition of the maternal gastrointestinal microbiome as a predictor of neonatal birth weight.Pediatric research · 2023Article
- Review
- Metagenomic characterization of the maternal prenatal gastrointestinal microbiome by pregravid BMI.Obesity (Silver Spring, Md.) · 2023Article
- Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists' Health Study.Archives of endocrinology and metabolism · 2023Article
- Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study.Frontiers in nutrition · 2023Article
- Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis.Cancer reports (Hoboken, N.J.) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMaternal obesity is a well-known risk factor for significant obstetric and neonatal complications. The influence of the gastrointestinal microbiome in the setting of maternal obesity during pregnancy is less understood. The purpose of this systematic review is to synthesize the literature on the relationships between maternal obesity and excessive gestational weight gain (EGWG) and the composition of maternal and child gastrointestinal microbiomes.
methodWe searched CINHAL, OVID Medline, Web of Science, and PubMed for relevant literature using medical subject heading terms related to obesity, pregnancy, and the gastrointestinal microbiome. We assessed 249 articles for potential inclusion using the preferred reporting items for systematic review and meta-analyses framework and deemed 11 articles as relevant for this review.
resultsMaternal obesity was associated with significant microbial changes in both maternal and infant fecal microbiome biospecimens including increases in
conclusionOur findings suggest that both maternal and child gastrointestinal microbiome composition is altered in the setting of maternal obesity and EGWG during pregnancy. Future microbiome studies should concentrate on the investigation of metagenomic sequencing to elucidate microbial function rather than solely taxonomic composition. More diverse populations of mothers should be sampled to address health disparities and adverse outcomes of underrepresented populations. Finally, analytic pipelines should be standardized across studies to aid in reproducibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.