Evidence map›Paper›PMID 31597401›Full record

ArticleGenes2019

Cholesteryl Ester Transfer Protein Genetic Variants Associated with Risk for Type 2 Diabetes and Diabetic Kidney Disease in Taiwanese Population.

Yu-Chuen Huang, Shih-Yin Chen, Shih-Ping Liu, Jane-Ming Lin, Hui-Ju Lin, Yu-Jie Lei, Yun-Chih Chung, Yu-Chi Chen, Yeh-Han Wang, Wen-Ling Liao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Journal of diabetes research · 2020
    Pooled it
  3. Gene-diet interaction betweenFrontiers in nutrition · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Lipids: A Major Culprit in Diabetic Nephropathy.Current diabetes reviews · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Association between LXR-Journal of diabetes research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yu-Chuen HuangSchool of Chinese Medicine, China Medical University, Taichung 404, Taiwan. yuchuen@mail.cmu.edu.tw.
Shih-Yin ChenSchool of Chinese Medicine, China Medical University, Taichung 404, Taiwan. chenshihy@mail.cmu.edu.tw.
Shih-Ping LiuCenter for Translational Medicine, China Medical University Hospital, Taichung 404, Taiwan. spliu@mail.cmu.edu.tw.
Jane-Ming LinSchool of Chinese Medicine, China Medical University, Taichung 404, Taiwan. d4301@seed.net.tw.
Hui-Ju LinSchool of Chinese Medicine, China Medical University, Taichung 404, Taiwan. irisluu2396@gmail.com.
Yu-Jie LeiDepartment of Medical Research, China Medical University Hospital, Taichung 404, Taiwan. yjlei0824@gmail.com.
Yun-Chih ChungDepartment of Public Health, China Medical University, Taichung 404, Taiwan. ai762928@gmail.com.
Yu-Chi ChenDepartment of Public Health, China Medical University, Taichung 404, Taiwan. s7911235@gmail.com.
Yeh-Han WangDepartment of Anatomical Pathology, Taipei Institute of Pathology, Taipei 103, Taiwan. yehanwang@gmail.com.
Wen-Ling LiaoCenter for Personalized Medicine, China Medical University Hospital, Taichung 404, Taiwan. wl0129@mail.cmu.edu.tw.
Fuu-Jen TsaiSchool of Chinese Medicine, China Medical University, Taichung 404, Taiwan. d0704@mail.cmuh.org.tw.
China Medical University · TWChina Medical University Hospital · TWTaipei Institute of Pathology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesteryl ester transfer protein (CETP) plays an important role in lipid metabolism. Low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of type 2 diabetes (T2D). This study investigated CETP gene variants to assess the risk of T2D and specific complications of diabetic kidney disease (DKD) and diabetic retinopathy. Towards this, a total of 3023 Taiwanese individuals (1383 without T2D, 1640 with T2D) were enrolled in this study. T2D mice (+Lepr

Indexed as

AdultAgedAged, 80 and overAllelesAnimalsAsian PeopleCholesterol Ester Transfer ProteinsCholesterol, HDLDiabetes Mellitus, Type 2Diabetic NephropathiesDiabetic RetinopathyFemaleGene FrequencyGenetic Predisposition to DiseaseGenetic VariationGenotypeCETP protein, humanCholesterol Ester Transfer ProteinsCholesterol, HDLCETPdiabetic kidney diseasediabetic retinopathyHDL-Ctype 2 diabetes

Identifiers

PMID31597401
PMCPMC6826370
OpenAlexW2979426750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.