Evidence map›Paper›PMID 31597394›Full record

ArticleAnimals : an open access journal from MDPI2019

Dietary Supplementation of 25-Hydroxycholecalciferol Improves Livability in Broiler Breeder Hens-Amelioration of Cardiac Pathogenesis and Hepatopathology.

Hsuan-Yu Lin, Pao-Chia Chou, Yu-Hui Chen, Lih-Shiuh Lai, Thau Kiong Chung, Rosemary L Walzem, San-Yuan Huang, Shuen-Ei Chen

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hsuan-Yu LinDepartment of Animal Science, National Chung Hsing University, Taichung 402, Taiwan.
Pao-Chia ChouDepartment of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.
Yu-Hui ChenDepartment of Animal Science, National Chung Hsing University, Taichung 402, Taiwan.
Lih-Shiuh LaiDepartment of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.
Thau Kiong ChungDSM Nutritional Products Asia Pacific, 117440, Singapore.
Rosemary L WalzemDepartment of Poultry Science, Texas A&M University, College Station, TX 77843, USA.
San-Yuan HuangDepartment of Animal Science, National Chung Hsing University, Taichung 402, Taiwan. syhuang@dragon.nchu.edu.tw.
Shuen-Ei ChenDepartment of Animal Science, National Chung Hsing University, Taichung 402, Taiwan. shueneic@dragon.nchu.edu.tw.
National Chung Hsing University · TWTexas A&M University · US

Funding

Ministry of Science and Technology, Taiwan MOST 106-2313-B-005-057Texas AgriLife 8738the Ministry of Education, Taiwan the iEGG and Animal Biotechnology Center and the Innovation and Development Center of Sustainable Agriculture from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project
6 · The paper itself

Abstract

A supplement of 69 μg 25-hydroxycholecalciferol (25-OH-D3)/kg feed increased livability in feed restricted (R-hens) broiler breeder hens by 9.9% and by 65.6% in hens allowed ad libitum feed intake (Ad-hens) in a feeding trial from age 26-60 weeks. Hens with higher bodyweight and/or adiposity suffered sudden death (SD) earlier in conjunction with compromised heart rhythms and over-ventilation. In the study with the same flock of hens, we demonstrate that 25-OH-D3 improved hen's livability and heart health by ameliorating systemic hypoxia, acidosis, and cardiac pathological hypertrophy through calcineurin-NFAT4c signaling and MHC- expression in association with reduced plasma triacylglycerol and hepatic steatosis and fibrosis (

Indexed as

25-hydroxycholecalciferolbroiler breeder henscardiac hypertrophyhepatic steatosissudden death

Identifiers

PMID31597394
PMCPMC6826734
OpenAlexW2979612043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.