Evidence map›Paper›PMID 31597327›Full record

ReviewNutrients2019

Dietary Compounds for Targeting Prostate Cancer.

Seungjin Noh, Eunseok Choi, Cho-Hyun Hwang, Ji Hoon Jung, Sung-Hoon Kim, Bonglee Kim

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Antibacterial Mechanism of Linalool againstFoods (Basel, Switzerland) · 2022
    Article
  5. Article
  6. The Role of DACT Family Members in Tumorigenesis and Tumor Progression.International journal of biological sciences · 2022
    Review
  7. Article
  8. Article
  9. Recent findings on the role of fungal products in the treatment of cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Seungjin NohCollege of Korean Medicine, Kyung Hee University, Seoul 02453, Korea. nohapril@khu.ac.kr.
Eunseok ChoiCollege of Korean Medicine, Kyung Hee University, Seoul 02453, Korea. eschoi1210@khu.ac.kr.
Cho-Hyun HwangCollege of Korean Medicine, Kyung Hee University, Seoul 02453, Korea. chohyun.hwang@khu.ac.kr.
Ji Hoon JungDepartment of Pathology, College of Korean Medicine, Graduate School, Kyung Hee University, Seoul 02453, Korea. johnsperfume@khu.ac.kr.
Sung-Hoon KimDepartment of Pathology, College of Korean Medicine, Graduate School, Kyung Hee University, Seoul 02453, Korea. sungkim7@khu.ac.kr.
Bonglee KimCollege of Korean Medicine, Kyung Hee University, Seoul 02453, Korea. bongleekim@khu.ac.kr.
Kyung Hee University · KR

Funding

(2019) URP program of College of Korean Medicine, Kyung Hee University 2019the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-2016R1D1A1B03933656
6 · The paper itself

Abstract

Prostate cancer is the third most common cancer worldwide, and the burden of the disease is increased. Although several chemotherapies have been used, concerns about the side effects have been raised, and development of alternative therapy is inevitable. The purpose of this study is to prove the efficacy of dietary substances as a source of anti-tumor drugs by identifying their carcinostatic activities in specific pathological mechanisms. According to numerous studies, dietary substances were effective through following five mechanisms; apoptosis, anti-angiogenesis, anti-metastasis, microRNA (miRNA) regulation, and anti-multi-drug-resistance (MDR). About seventy dietary substances showed the anti-prostate cancer activities. Most of the substances induced the apoptosis, especially acting on the mechanism of caspase and poly adenosine diphosphate ribose polymerase (PARP) cleavage. These findings support that dietary compounds have potential to be used as anticancer agents as both food supplements and direct clinical drugs.

Indexed as

DietAnticarcinogenic AgentsApoptosisCaspase InhibitorsDrug Resistance, MultipleHumansMaleMicroRNAsNeoplasm MetastasisNeovascularization, PathologicPhytochemicalsPoly(ADP-ribose) Polymerase InhibitorsProstatic NeoplasmsAnticarcinogenic AgentsCaspase InhibitorsMicroRNAsPhytochemicalsPoly(ADP-ribose) Polymerase Inhibitorsangiogenesisapoptosisdietary compoundsmetastasisMiRNAmulti drug resistancenatural compoundsprostate cancer

Identifiers

PMID31597327
PMCPMC6835786
OpenAlexW2980169991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.