Evidence map›Paper›PMID 31597248›Full record

ArticleSensors (Basel, Switzerland)2019

Fabrication of a Monolithic Lab-on-a-Chip Platform with Integrated Hydrogel Waveguides for Chemical Sensing.

Maria Leilani Torres-Mapa, Manmeet Singh, Olga Simon, Jose Louise Mapa, Manan Machida, Axel Günther, Bernhard Roth, Dag Heinemann, Mitsuhiro Terakawa, Alexander Heisterkamp

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  4. Review
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  7. Article
  8. Review
  9. Toward Tunable Protein-Driven Hydrogel Lens.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Leilani Torres-MapaInstitute of Quantum Optics, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. torres@iqo.uni-hannover.de.ORCID 0000-0003-2761-9586
Manmeet SinghInstitute of Quantum Optics, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. manmeet158@outlook.com.ORCID 0000-0003-4886-1697
Olga SimonLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany. diosima13@gmail.com.
Jose Louise MapaInstitute of Quantum Optics, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. louise.mapa@gmail.com.
Manan MachidaSchool of Integrated Design Engineering, Keio University, Yokohama 223-8522, Japan. m.machida@tera.elec.keio.ac.jp.
Axel GüntherHannover Centre for Optical Technologies, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. axel.guenther@email.de.
Bernhard RothHannover Centre for Optical Technologies, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. bernhard.roth@hot.uni-hannover.de.ORCID 0000-0001-9389-7125
Dag HeinemannLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany. d.heinemann@lzh.de.
Mitsuhiro TerakawaSchool of Integrated Design Engineering, Keio University, Yokohama 223-8522, Japan. terakawa@elec.keio.ac.jp.
Alexander HeisterkampInstitute of Quantum Optics, Gottfried Wilhelm Leibniz University Hannover, 30167 Hannover, Germany. heisterkamp@iqo.uni-hannover.de.ORCID 0000-0001-8770-0859

Funding

Bundesministerium für Bildung und Forschung 13N14085Deutsche Forschungsgemeinschaft EXC 2177Deutsche Forschungsgemeinschaft EXC 62
6 · The paper itself

Abstract

Hydrogel waveguides have found increased use for variety of applications where biocompatibility and flexibility are important. In this work, we demonstrate the use of polyethylene glycol diacrylate (PEGDA) waveguides to realize a monolithic lab-on-a-chip device. We performed a comprehensive study on the swelling and optical properties for different chain lengths and concentrations in order to realize an integrated biocompatible waveguide in a microfluidic device for chemical sensing. Waveguiding properties of PEGDA hydrogel were used to guide excitation light into a microfluidic channel to measure the fluorescence emission profile of rhodamine 6G as well as collect the fluorescence signal from the same device. Overall, this work shows the potential of hydrogel waveguides to facilitate delivery and collection of optical signals for potential use in wearable and implantable lab-on-a-chip devices.

Indexed as

Biosensing TechniquesLab-On-A-Chip DevicesFluorescenceHydrogelsMicrofluidicsPolyethylene GlycolsPrinting, Three-DimensionalRhodaminesHydrogelspoly(ethylene glycol)diacrylatePolyethylene Glycolsrhodamine 6GRhodamines3D printingfluorescencehydrogelsmicrofluidicswaveguide

Identifiers

PMID31597248
PMCPMC6806100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.