ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020
Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Sex and body size disparities under MELD 3.0: Evaluation of persisting gaps in liver transplant access.Hepatology (Baltimore, Md.) · 2026Article
- Sex-based survival disparities persist in liver transplantation: MELD 3.0 fails to improve survival for waitlisted women.Frontiers in transplantation · 2026Article
- Update on Organ Allocation and Liver Transplantation.Gastroenterology & hepatology · 2025Article
- Sex-based disparities in liver transplantation: Evidence from a nationwide Italian cohort.JHEP reports : innovation in hepatology · 2025Article
- Review
- Maximizing utility of nondirected living liver donor grafts using machine learning.Frontiers in immunology · 2023Article
- Liver simulated allocation model does not effectively predict organ offer decisions for pediatric liver transplant candidates.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021Article
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2 authors.
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Abstract
Height explains a substantial proportion of gender-based disparity in waitlist mortality among liver transplant candidates. We sought to identify a clinically relevant height cutoff below which waitlist mortality increases significantly. We examined all nonstatus one adult liver transplant candidates from 2010 to 2014. We used a recursive application of the minimum P value approach with univariate competing risk regressions (deceased donor liver transplantation as the competing risk) to detect differences in waitlist mortality with regards to height. Of 69 883 candidates, 36% (24 819) were women and 64% (45 064) were men. Median height for all was 173 cm: 163 cm in women, 178 cm in men. The optimal search method of recursively evaluating smaller height intervals yielded 166 cm as the optimal height cutoff. Using height <166 cm as the cutoff, 72% of women and 9% of men met criteria. Compared to candidates ≥166 cm, "short stature" candidates had higher rates of death/delisting (28% vs 24%) and lower rates of transplantation (38% vs 44%) (P < .01 for both). After adjustment for clinical and demographic characteristics, height <166 cm remained associated with an 8% increased risk of waitlist mortality (95% CI 1.03-1.14, P < .01). Short candidate height may be a motivation to explore split livers or living donors as accelerated liver transplantation options.
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