Evidence map›Paper›PMID 31596607›Full record

ArticleAmerican journal of physiology. Cell physiology2019

Phosphorylation of eukaryotic initiation factor 4E is dispensable for skeletal muscle hypertrophy.

Vandre C Figueiredo, Davis A Englund, Ivan J Vechetti, Alexander Alimov, Charlotte A Peterson, John J McCarthy

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Emerging role of TAK1 in the regulation of skeletal muscle mass.BioEssays : news and reviews in molecular, cellular and developmental biology · 2023
    Review
  3. Review
  4. Article
  5. Article
  6. Targeting cancer via ribosome biogenesis: the cachexia perspective.Cellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vandre C FigueiredoDepartment of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-3012-7905
Davis A EnglundDepartment of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
Ivan J VechettiDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.
Alexander AlimovDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.
Charlotte A PetersonDepartment of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
John J McCarthyDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.
University of Kentucky · US

Funding

NRSA Training CoreTL1TR001997 · NCATS · UNIVERSITY OF KENTUCKY · PI PENDERGAST, JULIE S, STOOPS, WILLIAM WALTON · 2016 to 2025
$4.2M
The role of satellite cells in adult skeletal muscle growth and maintenanceR01AR060701 · NIAMS · UNIVERSITY OF KENTUCKY · PI MCCARTHY, JOHN JOSEPH, PETERSON, CHARLOTTE A. · 2010 to 2019
$3.3M
The effects of exercise on satellite cell dynamics during agingR01AG049806 · NIA · UNIVERSITY OF KENTUCKY · PI MCCARTHY, JOHN JOSEPH, PETERSON, CHARLOTTE A. · 2016 to 2020
$1.8M
NCATS NIH HHS TL1 TR001997NIAMS NIH HHS R01 AR060701NIA NIH HHS R01 AG049806
6 · The paper itself

Abstract

The eukaryotic initiation factor 4E (eIF4E) is a major mRNA cap-binding protein that has a central role in translation initiation. Ser

Indexed as

Protein BiosynthesisAnimalsBiomechanical PhenomenaCyclin D1Eukaryotic Initiation Factor-4EFemaleGene Expression RegulationGene Knock-In TechniquesHypertrophyMaleMiceMice, Inbred C57BLMuscle, SkeletalNuclear ProteinsOrganelle BiogenesisPhosphorylationCcnd1 protein, mouseCyclin D1eIF4E protein, mouseEukaryotic Initiation Factor-4EMyc protein, mouseNuclear ProteinsProto-Oncogene Proteins c-mycRNA, RibosomalSerineprotein synthesisribosome biogenesisskeletal muscle growthtranslation

Identifiers

PMID31596607
PMCPMC6962521
OpenAlexW2979702754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.