ArticleHuman brain mapping2020
Short-term plasticity following motor sequence learning revealed by diffusion magnetic resonance imaging.
Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Specific Skilled Motor Versus General Exercise Training on Peripheral Muscle and Central Brain Alterations in Patients with Recurrent Low Back Pain
Neural Correlates of Multisensory Stimulation in Healthy Older Adults
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuronal substrates of motor impairment after subcortical ischemic stroke: a functional neuroimaging meta-analysis.Brain structure & function · 2025Pooled it
- Rapid neuroplasticity changes and response to intravenous ketamine: a randomized controlled trial in treatment-resistant depression.Translational psychiatry · 2023Trial
- Divergent Multimodal Age-Association Profiles Across the Human Brain.Nature communications · 2026Article
- Local and global microstructural and functional thalamomotor connectivity alterations in Parkinson's disease following motor learning.NPJ Parkinson's disease · 2026Article
- Distinct Physiological Mechanisms Drive Grey Matter Plasticity in Complex Versus Simple Sequence Learning.Human brain mapping · 2026Article
- Integrated anatomical and functional connectivity mapping in episodic migraine: a spectral graph theory approach.Scientific reports · 2026Article
- The effects of a second pregnancy on women's brain structure and function.Nature communications · 2026Article
- Neural network plasticity in Parkinson's disease: the impact of exercise-driven modulation.Frontiers in rehabilitation sciences · 2026Article
- The neuro-psychological dimensions of piano interaction: from mental health therapy to intelligent systems.Frontiers in psychology · 2026Review
- Longitudinal changes in brain asymmetry track lifestyle and disease.Nature communications · 2025Article
- Continuous Diffusion-Detected Neuroplasticity during Motor Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neural adaptations in short-term learning of sign language revealed by fMRI and DTI.Scientific reports · 2025Article
- Tutorial: a guide to diffusion MRI and structural connectomics.Nature protocols · 2025Review
- Distributed and gradual microstructure changes are associated with the emergence of behavioural benefit from memory reactivation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Review
- Associative white matter tracts selectively predict sensorimotor learning.Communications biology · 2024Article
- Training-related changes in neural beta oscillations associated with implicit and explicit motor sequence learning.Scientific reports · 2024Article
- Early excitatory-inhibitory cortical modifications following skill learning are associated with motor memory consolidation and plasticity overnight.Nature communications · 2024Article
- Immediate effect of quadri-pulse stimulation on human brain microstructures and functions.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- The importance of observing the master's hand: Action Observation Training promotes the acquisition of new musical skills.Frontiers in neurology · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current noninvasive methods to detect structural plasticity in humans are mainly used to study long-term changes. Diffusion magnetic resonance imaging (MRI) was recently proposed as a novel approach to reveal gray matter changes following spatial navigation learning and object-location memory tasks. In the present work, we used diffusion MRI to investigate the short-term neuroplasticity that accompanies motor sequence learning. Following a 45-min training session in which participants learned to accurately play a short sequence on a piano keyboard, changes in diffusion properties were revealed mainly in motor system regions such as the premotor cortex and cerebellum. In a second learning session taking place immediately afterward, feedback was given on the timing of key pressing instead of accuracy, while participants continued to learn. This second session induced a different plasticity pattern, demonstrating the dynamic nature of learning-induced plasticity, formerly thought to require months of training in order to be detectable. These results provide us with an important reminder that the brain is an extremely dynamic structure. Furthermore, diffusion MRI offers a novel measure to follow tissue plasticity particularly over short timescales, allowing new insights into the dynamics of structural brain plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.