ArticleJournal of applied oral science : revista FOB2019
A comparison of the sealing abilities between Biodentine and MTA as root-end filling materials and their effects on bone healing in dogs after periradicular surgery.
Article in Journal of applied oral science : revista FOB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Autologous Dental Pulp Stem Cell Transplantation for Mature Teeth With Apical Periodontitis and Root Perforation: Clinical and Radiographic Outcomes in Two Cases.Case reports in dentistry · 2026Article
- Endodontic Re-Surgery With Simultaneous Recession Coverage Using a Modified Flap Design After Failed Primary Apicoectomy: A Case Report.Clinical case reports · 2025Article
- Review of Approaches to the Management of Vertical Dental Root Fractures and Tooth Preservation.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Biocompatibility of mineral trioxide aggregate and biodentine as root-end filling materials: an in vivo study.Scientific reports · 2024Article
- Root-filling materials for endodontic surgery: biological and clinical aspects.Biomaterial investigations in dentistry · 2024Review
- Clinical application of calcium silicate-based bioceramics in endodontics.Journal of translational medicine · 2023Review
- Comparison of three different biomaterials used in in vitro molar apexification models.BMC oral health · 2023Article
- Real-time evaluation of the biocompatibility of calcium silicate-based endodontic cements: An in vitro study.Clinical and experimental dental research · 2023Article
- Bioceramics in Endodontics: Updates and Future Perspectives.Bioengineering (Basel, Switzerland) · 2023Review
- Article
- Effectiveness of different root-end filling materials in modern surgical endodontic treatment: A systematic review and network meta-analysis.Journal of dental sciences · 2022Article
- An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy.International journal of dentistry · 2022Review
- Biocompatibility and Osteogenic Potential of Calcium Silicate-Based Cement Combined with Enamel Matrix Derivative: Effects on Human Bone Marrow-Derived Stem Cells.Materials (Basel, Switzerland) · 2021Article
- Effect of exposure to etidronic acid on the bond strength of calcium silicate-based cements after 1 and 21 days: an in vitro study.BMC oral health · 2021Article
- Void characteristics and tortuosity of calcium silicate-based cements for regenerative endodontics: a micro-computed tomography analysis.BMC oral health · 2021Article
- Novel nanographene oxide-calcium phosphate cement inhibits Enterococcus faecalis biofilm and supports dental pulp stem cells.Journal of orthopaedic surgery and research · 2021Article
- Review
- Micro-computed tomographic evaluation of the flow and filling ability of endodontic materials using different test models.Restorative dentistry & endodontics · 2020Article
- Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the sealing ability and biocompatibility of Biodentine with mineral trioxide aggregate (MTA) when used as root-end filling materials. METHODOLOGY: The Cell Counting Kit-8 (CCK-8) assay was used to compare the cytotoxicity of MTA and Biodentine. Twenty-one extracted teeth with a single canal were immersed in an acidic silver nitrate solution after root-end filling. Then, the volume and depth of silver nitrate that infiltrated the apical portion of the teeth were analyzed using micro-computed tomography (micro-CT). Seventy-two roots from 3 female beagle dogs were randomly distributed into 3 groups and apical surgery was performed. After six months, the volume of the bone defect surrounding these roots was analyzed using micro-CT.
resultsBased on the results of the CCK-8 assay, MTA and Biodentine did not show statistically significant differences in cytotoxicity (P>0.05). The volume and the depth of the infiltrated nitrate solution were greater in the MTA group than in the Biodentine group (P<0.05). The volume of the bone defect was larger in the MTA group than in the Biodentine group. However, the difference was not significant (P>0.05). The volumes of the bone defects in the MTA and Biodentine groups were smaller than the group without any filling materials (P<0.05).
conclusionsMTA and Biodentine exhibited comparable cellular biocompatibility. Biodentine showed a superior sealing ability to MTA in root-end filling. Both Biodentine and MTA promoted periradicular bone healing in beagle dog periradicular surgery models.
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