Evidence map›Paper›PMID 31596219›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

The Effects of Transgender Hormone Therapy on Sleep and Breathing: A Case Series.

Brian D Robertson, Brian S Lerner, Jacob F Collen, Patrick R Smith

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Images: Irregular sleep-wake rhythm disorder in transgender individuals.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Gender identity and transition: relationships with sleep disorders in US youth.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  10. Sex and gender in respiratory physiology.European respiratory review : an official journal of the European Respiratory Society · 2021
    Article
  11. Article
  12. Gender Issues in Obstructive Sleep Apnea.The Yale journal of biology and medicine · 2021
    Review
  13. Article
  14. On Not Knowing What We Don't Know to Knowing What We Don't Know: Obstructive Sleep Apnea in the Transgender Community.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brian D RobertsonWalter Reed National Military Medical Center-Bethesda, Bethesda, Maryland.
Brian S LernerWalter Reed National Military Medical Center-Bethesda, Bethesda, Maryland.
Jacob F CollenUniformed Services University of the Health Sciences, Bethesda, Maryland.
Patrick R SmithWalter Reed National Military Medical Center-Bethesda, Bethesda, Maryland.
Walter Reed National Military Medical Center · USUniformed Services University of the Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

None: The effect of hormone therapy on sleep-disordered breathing in transgender patients has not been described. We present three cases of patients undergoing gender reassignment and treated with hormone replacement. The first case was a transgender woman (assigned male at birth) with a prolonged history of severe obstructive sleep apnea (OSA) that resolved following initiation of female sex hormones. The second and third cases both address transgender males (assigned female at birth) in whom OSA developed following initiation of male sex hormones (with pretreatment polysomnography documenting absence of OSA). The growing interest in transgender health warrants further evaluation of the effects of related therapies on sleep and sleep-disordered breathing.

Indexed as

Transgender PersonsAdolescentAdultAndrogensContinuous Positive Airway PressureEstradiolEstrogensFemaleHumansMaleMiddle AgedPolysomnographySleep Apnea, ObstructiveSleep Apnea SyndromesTestosteroneTreatment OutcomeAndrogensEstradiolEstrogensTestosterone

Identifiers

PMID31596219
PMCPMC6778344
OpenAlexW2981181664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.