Evidence map›Paper›PMID 31596214›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Sensitivity and Specificity of the Modified Epworth Sleepiness Scale in Children With Craniopharyngioma.

Valerie McLaughlin Crabtree, Kimberly Lauren Klages, April Sykes, Merrill S Wise, Zhaohua Lu, Daniel Indelicato, Thomas E Merchant, Yvonne Avent, Belinda N Mandrell

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  4. Progression of mild sleep-disordered breathing in children managed with watchful waiting.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
  5. Approach to the patient with acquired hypothalamic syndrome.The Journal of clinical endocrinology and metabolism · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Valerie McLaughlin CrabtreeDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Kimberly Lauren KlagesDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee.
April SykesDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Merrill S WiseMethodist Healthcare Sleep Disorders Center, Memphis, Tennessee.
Zhaohua LuDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Daniel IndelicatoUniversity of Florida Health Proton Therapy Institute, Jacksonville, Florida.
Thomas E MerchantDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Yvonne AventDepartment of Pediatric Medicine, Division of Nursing Research, St. Jude Children's Research Hospital, Memphis, Tennessee.
Belinda N MandrellDepartment of Pediatric Medicine, Division of Nursing Research, St. Jude Children's Research Hospital, Memphis, Tennessee.
St. Jude Children's Research Hospital · USMethodist Healthcare · USUniversity of Florida Health · USUniversity of Memphis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesChildren with craniopharyngioma are at risk for excessive daytime sleepiness (EDS). Multiple Sleep Latency Testing (MSLT) is the gold standard for objective evaluation of EDS; however, it is time and resource intensive. We compared the reliability, sensitivity, and specificity of the modified Epworth Sleepiness Scale (M-ESS) and MSLT in monitoring EDS in children with craniopharyngioma.

methodsSeventy patients (ages 6 to 20 years) with craniopharyngioma completed the M-ESS and were evaluated by polysomnography and MSLT. Evaluations were made after surgery, if performed, and before proton therapy.

resultsMSLT revealed that 66 participants (81.8%) had EDS, as defined by a mean sleep latency (MSL) < 10 minutes, with only 28.8% reporting EDS on the M-ESS by using a cutoff score of 10. The M-ESS demonstrated adequate internal consistency and specificity (91.7%) but poor sensitivity (33.3%) with the established cutoff score of 10. A cutoff score of 6 improved the sensitivity to 64.8% but decreased the specificity to 66.7%.

conclusionsPatients with craniopharyngioma are at high risk for EDS, as documented objectively on the MSLT, but they frequently do not recognize or accurately report their sleepiness. Future sleep studies should investigate whether specific items or alternative self- and parent-reported measures of sleepiness may have greater clinical utility in monitoring sleepiness in this population.

Indexed as

AdolescentAdultChildCraniopharyngiomaDisorders of Excessive SomnolenceFemaleHumansMalePituitary NeoplasmsPolysomnographyReproducibility of ResultsSensitivity and SpecificitySleepinessSleep LatencyYoung AdultCNS tumorcraniopharyngiomaexcessive daytime sleepiness (EDS)Modified Epworth Sleepiness ScaleMultiple Sleep Latency Testpediatrics

Identifiers

PMID31596214
PMCPMC6778340
OpenAlexW2980503102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.