Evidence map›Paper›PMID 31596123›Full record

SynthesisThe British journal of radiology2019

Accuracy of multiparametric magnetic resonance imaging for detecting extracapsular extension in prostate cancer: a systematic review and meta-analysis.

Fan Zhang, Chen-Lu Liu, Qian Chen, Sheng-Chao Shao, Shuang-Qing Chen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Comparison ofFrontiers in oncology · 2024
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Maximal radial distance for predicting extraprostatic extension of prostate cancer: a histopathological-radiological study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fan ZhangDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China.
Chen-Lu LiuDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China.
Qian ChenDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China.
Sheng-Chao ShaoDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China.
Shuang-Qing ChenDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the diagnostic accuracy of multiparametric MRI (mpMRI) for detecting extracapsular extension (ECE) in patients with prostate cancer (PCa). METHODS AND MATERIALS: We searched MEDLINE, PubMed, Embase and the Cochrane library up to December 2018. We included studies that used mpMRI to differentiate ECE from organ-confined PCa with a combination of

resultsA total of 17 studies that comprised 3374 participants were included. The pooled data showed a sensitivity of 0.55 (95% confidence interval 0.43, 0.66]) and specificity of 0.87 (95% confidence interval 0.82, 0.91) for extracapsular extension detection in PCa.

conclusionFirst, our meta-analysis shows moderate sensitivity and high specificity for mpMRI to differentiate ECE from organ-confined prostate cancer before surgery. Second, our meta-analysis shows that mpMRI had no significant differences in performance compared with the former meta-analysis with use of ADVANCES IN KNOWLEDGE: It is the first meta-analysis to evaluate the accuracy of mpMRI in combination of

Indexed as

Confidence IntervalsContrast MediaDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMalePreoperative CareProstateProstatectomyProstatic NeoplasmsROC CurveSensitivity and SpecificityContrast Media

Identifiers

PMID31596123
PMCPMC6913368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.