Evidence map›Paper›PMID 31596113›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2019

Rats are unable to discriminate quinine from diverse bitter stimuli.

Laura E Martin, Kristen E Kay, Ann-Marie Torregrossa

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura E MartinDepartment of Psychology, State University of New York at Buffalo, Buffalo, New York.
Kristen E KayDepartment of Psychology, State University of New York at Buffalo, Buffalo, New York.
Ann-Marie TorregrossaDepartment of Psychology, State University of New York at Buffalo, Buffalo, New York.
University at Buffalo, State University of New York · US

Funding

Salivary Protein Influence on Taste and FeedingR01DC016869 · NIDCD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI TORREGROSSA, ANN-MARIE · 2019 to 2023
$1.8M
NIDCD NIH HHS R01 DC016869
6 · The paper itself

Abstract

Compounds described by humans as "bitter" are sensed by a family of type 2 taste receptors (T2Rs). Previous work suggested that diverse bitter stimuli activate distinct receptors, which might allow for perceptually distinct tastes. Alternatively, it has been shown that multiple T2Rs are expressed on the same taste cell, leading to the contrary suggestion that these stimuli produce a unitary perception. Behavioral work done to address this in rodent models is limited to Spector and Kopka (Spector AC, Kopka SL.

Indexed as

TasteAnimalsCycloheximideDose-Response Relationship, DrugMalePropylthiouracilQuaternary Ammonium CompoundsQuinineRandom AllocationRatsRats, Long-EvansStimulation, ChemicalSucroseCycloheximidedenatoniumPropylthiouracilQuaternary Ammonium CompoundsQuinineSucrosesucrose octaacetatebitter discriminationpsychophysicsrattaste

Identifiers

PMID31596113
PMCPMC6957374
OpenAlexW2979526968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.