Evidence map›Paper›PMID 31595909›Full record

ArticleChemical communications (Cambridge, England)2019

A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission.

Dipendra Dahal, Lucas McDonald, Sabita Pokhrel, Sailaja Paruchuri, Michael Konopka, Yi Pang

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dipendra DahalDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.ORCID http://orcid.org/0000-0002-4153-5154
Lucas McDonaldDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.
Sabita PokhrelDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.
Sailaja ParuchuriDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.
Michael KonopkaDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.ORCID http://orcid.org/0000-0002-2194-6300
Yi PangDepartment of Chemistry, The University of Akron, Akron, OH 44325, USA. yp5@uakron.edu.ORCID http://orcid.org/0000-0001-7275-4563

Funding

NIR-Emitting Fluorescent Probes with Large Stokes Shift for Improved Zebrafish Neuromast ImagingR15GM126438 · NIGMS · UNIVERSITY OF AKRON · PI PANG, YI · 2018 to 2018
$417k
NIGMS NIH HHS R15 GM126438
6 · The paper itself

Abstract

There are a limited number of near-infrared (NIR) emitting (λem = 700-900 nm) molecular probes for imaging applications. A NIR-emitting probe that exhibits emission at ∼800 nm with a large Stokes shift was synthesized and found to exhibit excellent selectivity towards mitochondria for live-cell imaging. The photophysical properties were attributed to an excited "cyanine structure" via intramolecular charge transfer (ICT) involving a phenol group.

Indexed as

Optical ImagingCarbocyaninesCell LineFibroblastsFluorescent DyesHumansInfrared RaysLungMolecular StructureOligodendrogliaPhenolsSpectrometry, FluorescenceCarbocyaninesFluorescent DyesPhenols

Identifiers

PMID31595909
PMCPMC6918678

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.