Evidence map›Paper›PMID 31595836›Full record

ArticleJournal of the American Heart Association2019

Renal Dysfunction and In-Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy.

Zhen-Zhen Rao, Hong-Qiu Gu, Xian-Wei Wang, Xue-Wei Xie, Xin Yang, Chun-Juan Wang, Xingquan Zhao, Ying Xian, Yi-Long Wang, Zi-Xiao Li and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Zhen-Zhen RaoInstitute of Molecular Medicine, Yingjie Center Peking University Beijing China.
Hong-Qiu GuChina National Clinical Research Center for Neurological Diseases Beijing China.
Xian-Wei WangChina National Clinical Research Center for Neurological Diseases Beijing China.
Xue-Wei XieChina National Clinical Research Center for Neurological Diseases Beijing China.
Xin YangChina National Clinical Research Center for Neurological Diseases Beijing China.
Chun-Juan WangChina National Clinical Research Center for Neurological Diseases Beijing China.
Xingquan ZhaoChina National Clinical Research Center for Neurological Diseases Beijing China.
Ying XianDuke Clinical Research Institute Duke University Medical Center Durham NC.
Yi-Long WangChina National Clinical Research Center for Neurological Diseases Beijing China.
Zi-Xiao LiChina National Clinical Research Center for Neurological Diseases Beijing China.
Rui-Ping XiaoInstitute of Molecular Medicine, Yingjie Center Peking University Beijing China.
Yong-Jun WangChina National Clinical Research Center for Neurological Diseases Beijing China.
Chinese Stroke Center Alliance investigators
National Clinical Research Center for Digestive Diseases · CNChinese Institute for Brain Research · CNPeking University · CNBeijing Tian Tan Hospital · CNCapital Medical University · CNDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The impact of estimated glomerular filtration rate (eGFR) on clinical short-term outcomes after stroke thrombolysis with tissue plasminogen activator remains controversial. Methods and Results We analyzed 18 320 ischemic stroke patients who received intravenous tissue plasminogen activator at participating hospitals in the Chinese Stroke Center Alliance between June 2015 and November 2017. Multivariate logistic regression models were used to evaluate associations between eGFR (<45, 45-59, 60-89, and ≥90 mL/min per 1.73 m

Indexed as

RegistriesAcute DiseaseAgedAged, 80 and overBrain IschemiaChinaDose-Response Relationship, DrugFemaleGlomerular Filtration RateHospital MortalityHumansInfusions, IntravenousKidney DiseasesMaleMiddle AgedRetrospective StudiesTissue Plasminogen Activatorglomerular filtration rateischemic strokeoutcomerenal functiontissue‐type plasminogen activator

Identifiers

PMID31595836
PMCPMC6818031
OpenAlexW2979776185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.