Evidence map›Paper›PMID 31595399›Full record

ArticleThe international journal of cardiovascular imaging2020

Relationship between left atrial strain, diastolic dysfunction and subclinical atrial fibrillation in patients with cryptogenic stroke: the SURPRISE echo substudy.

Flemming J Olsen, Louisa M Christensen, Derk W Krieger, Søren Højberg, Nis Høst, Finn M Karlsen, Jesper H Svendsen, Hanne Christensen, Tor Biering-Sørensen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06417112 (Can Left Atrial Strain Measurements, and Correlating Changes in Left Atrium Area and Volume Size, be Used as an Early Predictor of Atrial Fibrillation?), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06417112 completednot on this mapstarted 2023, after this paper: background citation

Can Left Atrial Strain Measurements, and Correlating Changes in Left Atrium Area and Volume Size, be Used as an Early Predictor of Atrial Fibrillation?

TypeobservationalSponsorHywel Dda Health BoardRan2023 to 2024Enrolled72ConditionsAtrial Fibrillation, HypertensionArmsTransthoracic Echocardiogram
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Atrial strain and occult atrial fibrillation in cryptogenic stroke patients: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
    Pooled it
  3. Pooled it
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  6. Trial
  7. Review
  8. Article
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  12. Review
  13. Assessment of left atrial function using two-dimensional speckle tracking echocardiography in cryptogenic stroke patients.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
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  16. Article
  17. Review
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  19. Expert opinion paper on cardiac imaging after ischemic stroke.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Review
  20. Assessment of the ability of the CHABMC cardiovascular disorders · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Flemming J OlsenCardiovascular Non-Invasive Imaging Research Laboratory (CIRL), Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Hellerup, Denmark. flemming.j.olsen@gmail.com.ORCID http://orcid.org/0000-0001-9511-8375
Louisa M ChristensenDepartment of Neurology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Derk W KriegerComprehensive Stroke Center, Mediclinic City Hospital, Dubai, United Arab Emirates.
Søren HøjbergDepartment of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Nis HøstDepartment of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Finn M KarlsenDepartment of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Jesper H SvendsenInstitute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hanne ChristensenDepartment of Neurology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Tor Biering-SørensenCardiovascular Non-Invasive Imaging Research Laboratory (CIRL), Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
University of Copenhagen · DKMohammed Bin Rashid University of Medicine and Health Sciences · AE

Funding

Hjerteforeningen 18-R125-A8534-22083
6 · The paper itself

Abstract

Paroxysmal atrial fibrillation (PAF) may be the cause of a substantial part of cryptogenic strokes (CS). Echocardiography could assist risk stratification for PAF to select patients in need of prolonged rhythm monitoring. We aimed to assess the value of left atrial (LA) strain and a revised diastolic dysfunction (DDF) model with LA strain for predicting PAF. This was a prospective study of 56 CS patients who had a cardiac monitor implanted for 3 year monitoring for PAF, and an echocardiogram performed prior to monitoring. Conventional echocardiography, global longitudinal strain (GLS) and LA strain were performed. LA speckle tracking provided the LA reservoir strain (LAs). Patients were stratified into high versus low LAs by ROC curves (28.2%), and this cut-off was used to refine DDF grading. During follow-up of median 20 months, 13 (23%) patients were diagnosed with PAF. No conventional echocardiographic parameters differed between patients who developed PAF and those without PAF. However, LAs was significantly impaired in PAF patients (LAs: 30 vs. 27% for non-PAF and PAF, p = 0.046). Low LAs significantly predicted PAF independent of LA volume and GLS [OR 5.88 (1.30; 26.55), p = 0.021]. Revised DDF grading significantly predicted PAF, even when adjusted for the CHADS

Indexed as

Atrial Function, LeftEchocardiographyVentricular Function, LeftAdultAgedAtrial FibrillationDiastoleFemaleHeart RateHumansMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesReproducibility of ResultsAtrial fibrillationAtrial strainCryptogenic strokeEchocardiography

Identifiers

PMID31595399
OpenAlexW2980307051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.