ArticleBiogerontology2020
Human ageing as a dynamic, emergent and malleable process: from disease-oriented to health-oriented approaches.
Article in Biogerontology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Ageing was never a singular problem in biology: implications for mechanisms, measurements and interventions.Biogerontology · 2026Review
- Investigating Aging and DNA Methylation: A Path to Improving Health Span?The Yale journal of biology and medicine · 2025Review
- The evolution of ageing: classic theories and emerging ideas.Biogerontology · 2024Review
- Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions.Aging and disease · 2024Review
- Mitochondrial Dysfunction: A Key Player in Brain Aging and Diseases.Current issues in molecular biology · 2024Review
- Informing the Cannabis Conjecture: From Life's Beginnings to Mitochondria, Membranes and the Electrome-A Review.International journal of molecular sciences · 2023Review
- Novel Strategy in Searching for Natural Compounds with Anti-Aging and Rejuvenating Potential.International journal of molecular sciences · 2023Article
- Relationships between anthropometric and body composition characteristics and age in Polish women over 60 as affected by their socioeconomic and health status and physical activity levels.Frontiers in physiology · 2023Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the decades, biogerontology has matured as a scientific discipline. Currently, a number of theoretical frameworks are available to researchers when interpreting empirical data. Despite the great progress that has been made, a comprehensive understanding of biological processes that shape ageing is lacking. Senescence is a dynamic, plastic and highly complex metaphenomenon whose aetiology remains unclear. The paucity of information notwithstanding, some researchers promote 'anti-ageing' drugs and formulae every now and again. The rationale behind this concept is that ageing can be reduced to a mixture of biochemical reactions. Furthermore, the distinction between ageing and disease has been questioned on the grounds that ageing is the root of age-related diseases. It has been claimed that disease-oriented approaches can help delay ageing and prevent age-related diseases. Although these methods seem incongruous from an evolutionary standpoint, they become popular amongst the public. Moreover, if ageing is classified as a disease, this situation is likely to be exacerbated. Therefore, it is important to recognise the limitations of these reductionist and disease-oriented approaches. Only holistic and evidence-based strategies might be useful in slowing down ageing and preventing age-related diseases in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.