Evidence map›Paper›PMID 31595257›Full record

ReviewPorto biomedical journal

Understanding the relevance of herb-drug interaction studies with special focus on interplays: a prerequisite for integrative medicine.

Swapnil P Borse, Devendra P Singh, Manish Nivsarkar

Abstract readReview
In one paragraph

Review in Porto biomedical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Assessment of Undergraduate Nursing Students' Understanding of Herbal Medicines and Herb-Drug Interactions in Riyadh, Saudi Arabia.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Frontiers in pharmacology · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Effects ofCurrent neuropharmacology · 2021
    Review
  17. Article
  18. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  19. Journal of parasitology research · 2021
    Article
  20. Drug metabolism and disposition: the biological fate of chemicals · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Swapnil P BorseDepartment of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Thaltej.
Devendra P SinghDepartment of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Thaltej.
Manish NivsarkarDepartment of Pharmacology and Toxicology, B.V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Thaltej.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrative medicine refers to the blending of conventional and evidence-based complementary medicines and therapies with the aim of using the most appropriate of either or both modalities for ultimate patient benefits. One of the major hurdles for the same is the chances of potential herb-drug interactions (HDIs). These HDIs could be beneficial or harmful, or even fatal; therefore, a thorough understanding of the eventualities of HDIs is essential so that a successful integration of the modern and complementary alternative systems of medicine could be achieved. Here, we summarize all the important points related to HDIs, including types, tools/methods for study, and prediction of the HDIs, along with a special focus on interplays between drug metabolizing enzymes and transporters. In addition, this article covers future perspective, with a focus on background endogenous players of interplays and approaches to predict the drug-disease-herb interactions so as to fetch the desired effects of these interactions.

Indexed as

Ayurvedadrug metabolizing enzymes–transporter interplaysherb–drug–disease interactionsintegrative medicine

Identifiers

PMID31595257
PMCPMC6726296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.