Evidence map›Paper›PMID 31594995›Full record

ArticleScientific reports2019

Maternal physical activity prevents the overexpression of hypoxia-inducible factor 1-α and cardiorespiratory dysfunction in protein malnourished rats.

Viviane O Nogueira, Luana D S Andrade, Reginaldo L Rocha-Júnior, Palloma E D Melo, Elisama Helvécio, Danilo A F Fontes, Tatiany P Romão, Carol G Leandro, João H Costa-Silva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Viviane O NogueiraLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
Luana D S AndradeLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
Reginaldo L Rocha-JúniorLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
Palloma E D MeloLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
Elisama HelvécioDepartamento de Entomologia, Centro de Pesquisas Aggeu Magalhães - FIOCRUZ, Recife, PE, Brazil.
Danilo A F FontesLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
Tatiany P RomãoDepartamento de Entomologia, Centro de Pesquisas Aggeu Magalhães - FIOCRUZ, Recife, PE, Brazil.
Carol G LeandroLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil.
João H Costa-SilvaLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco, Vitória de Santo Antão, PE, Brazil. joao.hcsilva@ufpe.br.
Universidade Federal de Pernambuco · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal physical activity attenuates cardiorespiratory dysfunctions and transcriptional alterations presented by the carotid body (CB) of rats. Rats performed physical activity and were classified as inactive/active. During gestation and lactation, mothers received either normoprotein (NP-17% protein) or low-protein diet (LP-8% protein). In offspring, biochemical serum levels, respiratory parameters, cardiovascular parameters and the mRNA expression of hypoxia-inducible factor 1-alpha (HIF-1α), tyrosine hydroxylase (TH) and purinergic receptors were evaluate. LP-inactive pups presented lower RF from 1

Indexed as

Prenatal Exposure Delayed EffectsAnimalsCardiorespiratory FitnessCardiovascular SystemCarotid BodyDiet, Protein-RestrictedFemaleGene Expression RegulationHumansHypoxia-Inducible Factor 1, alpha SubunitLactationMalnutritionMaternal Nutritional Physiological PhenomenaPhysical Conditioning, AnimalPregnancyRatsHif1a protein, ratHypoxia-Inducible Factor 1, alpha Subunit

Identifiers

PMID31594995
PMCPMC6783408
OpenAlexW2979328954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.