Evidence map›Paper›PMID 31594962›Full record

ArticleScientific reports2019

Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy.

Masayoshi Yamada, Yutaka Saito, Hitoshi Imaoka, Masahiro Saiko, Shigemi Yamada, Hiroko Kondo, Hiroyuki Takamaru, Taku Sakamoto, Jun Sese, Aya Kuchiba and 2 more

Registry-linked trialOpen access · goldAbstract readValidation Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05611151 (Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy), which is not on this map. Cited by 106 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 8 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05611151 nacompletednot on this mapstarted 2023, after this paper: background citation

Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy: Prospective, Randomized Clinical Performance Evaluation

TypeinterventionalSponsorNEC CorporationRan2023 to 2024Enrolled830ConditionsColorectal Cancer, Adenoma Colon, Polyp of ColonArmsComputer Aided Detection (CADe)
3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 8 syntheses or guidelines pooled it, 258 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Systematic Review and Meta-analysis of Convolutional Neural Network in the Diagnosis of Colorectal Polyps and Cancer.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Review
  10. Article
  11. Article
  12. Article
  13. Integration of Endocuff-Assisted and Computer-Aided Colonoscopy: A Meta-Analysis of Randomized Controlled Trials.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Masayoshi YamadaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan. masyamad@ncc.go.jp.
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Hitoshi ImaokaBiometrics Research Laboratories, NEC Corporation, Kanagawa, Japan.
Masahiro SaikoBiometrics Research Laboratories, NEC Corporation, Kanagawa, Japan.
Shigemi YamadaDivision of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.
Hiroko KondoDivision of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.
Hiroyuki TakamaruEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Taku SakamotoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Jun SeseArtificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.
Aya KuchibaBiostatistics Division, National Cancer Center, Tokyo, Japan.ORCID http://orcid.org/0000-0002-6786-3527
Taro ShibataBiostatistics Division, National Cancer Center, Tokyo, Japan.
Ryuji HamamotoDivision of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.
National Cancer Center Hospital East · JPRIKEN Center for Advanced Intelligence Project · JPNEC (Japan) · JPNational Cancer Center · USNational Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gaps in colonoscopy skills among endoscopists, primarily due to experience, have been identified, and solutions are critically needed. Hence, the development of a real-time robust detection system for colorectal neoplasms is considered to significantly reduce the risk of missed lesions during colonoscopy. Here, we develop an artificial intelligence (AI) system that automatically detects early signs of colorectal cancer during colonoscopy; the AI system shows the sensitivity and specificity are 97.3% (95% confidence interval [CI] = 95.9%-98.4%) and 99.0% (95% CI = 98.6%-99.2%), respectively, and the area under the curve is 0.975 (95% CI = 0.964-0.986) in the validation set. Moreover, the sensitivities are 98.0% (95% CI = 96.6%-98.8%) in the polypoid subgroup and 93.7% (95% CI = 87.6%-96.9%) in the non-polypoid subgroup; To accelerate the detection, tensor metrics in the trained model was decomposed, and the system can predict cancerous regions 21.9 ms/image on average. These findings suggest that the system is sufficient to support endoscopists in the high detection against non-polypoid lesions, which are frequently missed by optical colonoscopy. This AI system can alert endoscopists in real-time to avoid missing abnormalities such as non-polypoid polyps during colonoscopy, improving the early detection of this disease.

Indexed as

ColonoscopyDeep LearningColorectal NeoplasmsComputer SystemsHumansImage Processing, Computer-AssistedRetrospective StudiesSensitivity and Specificity

Identifiers

PMID31594962
PMCPMC6783454
OpenAlexW2979904523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.