Observational studyBMJ open2019
Global patterns and trends in the breast cancer incidence and mortality according to sociodemographic indices: an observational study based on the global burden of diseases.
Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO international clinical trial register database.Frontiers in oncology · 2025Pooled it
- A randomised online experimental study to compare responses to brief and extended surveys of health-related quality of life and psychosocial outcomes among women with breast cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Trial
- Global trends and disease burden of elderly male breast cancer, 1990-2021: a population-based study.Frontiers in endocrinology · 2026Article
- Global Patterns and Trends in Lifetime Risks of Developing and Dying from Cancer, 1990-2021.Health data science · 2026Article
- Sexual dysfunction in women who received breast cancer treatment: a cross-sectional study.Scientific reports · 2025Article
- Primary endocrine therapy versus surgery plus endocrine therapy for early-stage breast cancer in older women without frailty: a cost-effectiveness and value of implementation analysis.Health economics review · 2025Article
- The hidden pathway: biological aging as a mediator between diabetes and breast cancer risk: a Mendelian randomized study.Discover oncology · 2025Article
- The global burden of breast cancer among women of reproductive age: a comprehensive analysis.Scientific reports · 2025Article
- Two natural products from the seeds ofFrontiers in pharmacology · 2025Article
- Article
- Statin use as a moderator on the association between metformin and breast cancer risk in women with type 2 diabetes mellitus.Cancer & metabolism · 2024Article
- Epidemiological patterns of chronic kidney disease attributed to type 2 diabetes from 1990-2019.Frontiers in endocrinology · 2024Article
- Machine learning approaches for predicting 5-year breast cancer survival: A multicenter study.Cancer science · 2023Article
- Sonocatalytic Optimization of Titanium-Based Therapeutic Nanomedicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Disparities in breast cancer mortality among Latin American women: trends and predictions for 2030.BMC public health · 2023Article
- Role of Serum Lipids, Blood Glucose and Blood Pressure in Breast Cancer Risk for Women with Type 2 Diabetes Mellitus.Clinical epidemiology · 2023Article
- Screening Programs for Breast Cancer: Toward Individualized, Risk-Adapted Strategies of Early Detection.Cancer treatment and research · 2023Article
- Burden of breast cancer and attributable risk factors in the North Africa and Middle East region, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.Frontiers in oncology · 2023Article
- Evaluation of Lee-Carter model to breast cancer mortality prediction in China and Pakistan.Frontiers in oncology · 2023Article
- Burden of female breast cancer in the Middle East and North Africa region, 1990-2019.Archives of public health = Archives belges de sante publique · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDisparities in the global burden of breast cancer have been identified. We aimed to investigate recent patterns and trends in the breast cancer incidence and associated mortality. We also assessed breast cancer-related health inequalities according to socioeconomic development factors.
designAn observational study based on the Global Burden of Diseases.
methodsEstimates of breast cancer incidence and mortality during 1990-2016 were obtained from the Global Health Data Exchange database. Subsequently, data obtained in 2016 were described using the age-standardised and age-specific incidence, mortality and mortality-to-incidence (MI) ratios according to sociodemographic index (SDI) levels. Trends were assessed by measuring the annual percent change using the joinpoint regression. The Gini coefficients and concentration indices were used to identify between-country inequalities.
resultsCountries with higher SDI levels had worse disease incidence burdens in 2016, whereas inequalities in the breast cancer incidence had decreased since 1990. Opposite trends were observed in the mortality rates of high and low SDI countries. Moreover, the decreasing concentration indices, some of which became negative, among women aged 15-49 and 50-69 years suggested an increase in the mortality burdens in undeveloped regions. Conversely, inequality related to the MI ratio increased. In 2016, the MI ratios exhibited distinct gradients from high to low SDI regions across all age groups.
conclusionsThe patterns and trends in breast cancer incidence and mortality closely correlated with the SDI levels. Our findings highlighted the primary prevention of breast cancer in high SDI countries with a high disease incidence and the development of cost-effective diagnostic and treatment interventions for low SDI countries with poor MI ratios as the two pressing needs in the next decades.
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