Evidence map›Paper›PMID 31594854›Full record

ArticleScience signaling2019

The Ca

Christina K Go, Robert Hooper, Matthew R Aronson, Bryant Schultz, Taha Cangoz, Neeharika Nemani, Yi Zhang, Muniswamy Madesh, Jonathan Soboloff

Abstract read
In one paragraph

Article in Science signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Renalase stimulates aldosterone production via PMCA4b/cAMP in NCI-H295R cells.Journal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. The scramblase anoctamin 9 controls the immune response in lymphocytes.Cellular and molecular life sciences : CMLS · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Anoctamin 9 determines CaFrontiers in immunology · 2025
    Article
  7. Article
  8. Multifaceted control of T cell differentiation by STIM1.Trends in biochemical sciences · 2023
    Review
  9. Review
  10. Article
  11. CaInternational journal of molecular sciences · 2023
    Article
  12. Suppression of CaThe EMBO journal · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Plasma Membrane CaFunction (Oxford, England) · 2022
    Article
  18. The interplay between mitochondria and store-operated CaJournal of cellular and molecular medicine · 2021
    Review
  19. Review
  20. The Plasma Membrane CaCancers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Christina K GoFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0002-7716-8720
Robert HooperFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Matthew R AronsonFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0002-8871-8265
Bryant SchultzFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Taha CangozFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0002-0037-8201
Neeharika NemaniDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Yi ZhangDepartment of Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Muniswamy MadeshDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0001-6745-9092
Jonathan SoboloffFels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA. soboloff@temple.edu.ORCID 0000-0001-5192-1297
Temple University · US

Funding

Coordination of Pathophysiologic Endothelial Cell Signaling by ROSR01HL086699 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2008 to 2018
$4.3M
Spectral revelations of mitochondrial Ca2+ flux interactomeR01GM109882 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2014 to 2022
$3.3M
EGR-mediated STIM1-PMCA expression and function in T cell subsetsR01GM117907 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI SOBOLOFF, JONATHAN A · 2016 to 2019
$1.6M
Modulation of calcium signaling by changes in STIM expressionR01GM097335 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI SOBOLOFF, JONATHAN A · 2011 to 2015
$1.5M
NHLBI NIH HHS R01 HL086699NIGMS NIH HHS R01 GM097335NIGMS NIH HHS R01 GM109882NIGMS NIH HHS R01 GM117907
6 · The paper itself

Abstract

Ca

Indexed as

Calcium SignalingCalciumCell MembraneEndoplasmic ReticulumHEK293 CellsHumansJurkat CellsLuminescent ProteinsMicroscopy, FluorescenceNFATC Transcription FactorsORAI1 ProteinPlasma Membrane Calcium-Transporting ATPasesRNA InterferenceStromal Interaction Molecule 1CalciumLuminescent ProteinsNFATC Transcription FactorsORAI1 ProteinPlasma Membrane Calcium-Transporting ATPasesStromal Interaction Molecule 1

Identifiers

PMID31594854
PMCPMC6800072
OpenAlexW2979735628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.