Evidence map›Paper›PMID 31594816›Full record

ArticlemBio2019

Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes.

Mary-Louise Wilde, Tony Triglia, Danushka Marapana, Jennifer K Thompson, Alexei A Kouzmitchev, Hayley E Bullen, Paul R Gilson, Alan F Cowman, Christopher J Tonkin

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 77 citations in OpenAlex.

  1. MAHRP2 is required for tether formation and cytoadherence inFrontiers in cellular and infection microbiology · 2026
    Article
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  5. Article
  6. Applications of CRISPR in Parasitology.Current pharmaceutical biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. SPARK regulates AGC kinases central to thebioRxiv : the preprint server for biology · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. CRISPR-Cas9: Taming protozoan parasites with bacterial scissor.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mary-Louise WildeThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Tony TrigliaThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Danushka MarapanaThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Jennifer K ThompsonThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Alexei A KouzmitchevUtrecht University, Utrecht, Netherlands.
Hayley E BullenBurnet Institute, Melbourne, Australia.
Paul R GilsonBurnet Institute, Melbourne, Australia.
Alan F CowmanThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Christopher J TonkinThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia tonkin@wehi.edu.au.ORCID 0000-0002-7036-6222
The University of Melbourne · AUWalter and Eliza Hall Institute of Medical Research · AUBurnet Institute · AUUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the mechanisms behind host cell invasion by

Indexed as

EndocytosisAntigens, ProtozoanCatalytic DomainCyclic AMP-Dependent Protein KinasesErythrocytesHumansMembrane ProteinsPhosphorylationPlasmodium falciparumProtein Processing, Post-TranslationalProtozoan ProteinsAntigens, Protozoanapical membrane antigen I, PlasmodiumCyclic AMP-Dependent Protein KinasesMembrane ProteinsProtozoan ProteinsAMP-activated kinaseshost cell invasionmalariaPlasmodium falciparum

Identifiers

PMID31594816
PMCPMC6786871
OpenAlexW2979823670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.