Evidence map›Paper›PMID 31594809›Full record

ArticlemBio2019

Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy.

Sean Conlan, Anna F Lau, Clay Deming, Christine D Spalding, ShihQueen Lee-Lin, Pamela J Thomas, Morgan Park, John P Dekker, Karen M Frank, Tara N Palmore and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Genomic Insights Into the Mechanism of Carbapenem Resistance Dissemination in Enterobacterales From a Tertiary Public Heath Setting in South Asia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  5. Article
  6. Mobility ofMicrobial genomics · 2021
    Article
  7. Environmental Spread of Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Applied and environmental microbiology · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sean ConlanNational Human Genome Research Institute, Bethesda, Maryland, USA conlans@mail.nih.gov.ORCID 0000-0001-6848-3465
Anna F LauNational Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Clay DemingNational Human Genome Research Institute, Bethesda, Maryland, USA.
Christine D SpaldingNational Institutes of Health Clinical Center, Bethesda, Maryland, USA.
ShihQueen Lee-LinNational Human Genome Research Institute, Bethesda, Maryland, USA.
Pamela J ThomasNational Institutes of Health Intramural Sequencing Center (NISC), Rockville, Maryland, USA.
Morgan ParkNational Institutes of Health Intramural Sequencing Center (NISC), Rockville, Maryland, USA.
John P DekkerNational Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Karen M FrankNational Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Tara N PalmoreNational Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Julia A SegreNational Human Genome Research Institute, Bethesda, Maryland, USA.ORCID 0000-0001-6860-348X
National Human Genome Research Institute · USNational Institutes of Health Clinical Center · USNational Institutes of Health · USNational Institute of Allergy and Infectious Diseases · US

Funding

Microbial genomics of hospital-associated pathogensZIAHG200382 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI SEGRE, JULIA ANGELA · 2012 to 2025
$9.1M
Studies of the Human Microbiome in Clinical Center PatientsZIACL004042 · CLC · CLINICAL CENTER · PI PALMORE, TARA · 2014 to 2021
$0k
Investigation of Horizontal Transfer of Carbapenemase Gene in Gram Negative BacteriaZIACL080018 · CLC · CLINICAL CENTER · PI FRANK, KAREN · 2014 to 2022
$0k
Intramural NIH HHS ZIA CL004042Intramural NIH HHS ZIA CL080018Intramural NIH HHS ZIA HG200382
6 · The paper itself

Abstract

Antibiotics, which are used both to prevent and to treat infections, are a mainstay therapy for lifesaving procedures such as transplantation. For this reason, and many others, increased antibiotic resistance among human-associated pathogens, such as the carbapenem-resistant

Indexed as

Drug Resistance, Multiple, BacterialGene Transfer, HorizontalAnti-Bacterial AgentsAntibiotic ProphylaxisHematopoietic Stem Cell TransplantationHumansKlebsiella InfectionsKlebsiella pneumoniaePlasmidsSelection, GeneticTransplant RecipientsAnti-Bacterial Agentsantibiotic resistancecarbapenemsEnterobacteriaceaegenomesHGTKlebsiellaplasmids

Identifiers

PMID31594809
PMCPMC6786864
OpenAlexW2980281662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.