Evidence map›Paper›PMID 31594805›Full record

ArticleThe Journal of cell biology2019

An intrinsic compartmentalization code for peripheral membrane proteins in photoreceptor neurons.

Nycole A Maza, William E Schiesser, Peter D Calvert

Open access · greenAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Frontiers in molecular neuroscience · 2023
    Article
  5. Article
  6. Comparison of Ciliary Targeting of Two Rhodopsin-Like GPCRs: Role of C-Terminal Localization Sequences in Relation to Cilium Type.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  7. Functional compartmentalization of photoreceptor neurons.Pflugers Archiv : European journal of physiology · 2021
    Review
  8. Compartmentalization of Photoreceptor Sensory Cilia.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nycole A MazaCenter for Vision Research, Department of Ophthalmology and Visual Sciences, State University of New York Upstate Medical University, Syracuse, NY.ORCID 0000-0002-5947-8039
William E SchiesserDepartment of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA.
Peter D CalvertCenter for Vision Research, Department of Ophthalmology and Visual Sciences, State University of New York Upstate Medical University, Syracuse, NY calvertp@upstate.edu.ORCID 0000-0001-9162-4924
SUNY Upstate Medical University · USLehigh University · US

Funding

Supplement for ZetaSizer instrumentR01EY018421 · NEI · UPSTATE MEDICAL UNIVERSITY · PI CALVERT, PETER DEANE · 2007 to 2025
$6.2M
Construction and stability of photoreceptor outer segment discsR01EY028303 · NEI · UPSTATE MEDICAL UNIVERSITY · PI CALVERT, PETER DEANE · 2018 to 2022
$2.2M
High performance Orbitrap Fusion Lumos mass spectrometer for proteomics and metabolomic researchS10OD023617 · OD · UPSTATE MEDICAL UNIVERSITY · PI KNUTSON, BRUCE ALAN · 2018 to 2018
$1.1M
NEI NIH HHS R01 EY018421NEI NIH HHS R01 EY028303NIH HHS S10 OD023617
6 · The paper itself

Abstract

In neurons, peripheral membrane proteins are enriched in subcellular compartments, where they play key roles, including transducing and transmitting information. However, little is known about the mechanisms underlying their compartmentalization. To explore the roles of hydrophobic and electrostatic interactions, we engineered probes consisting of lipidation motifs attached to fluorescent proteins by variously charged linkers and expressed them in

Indexed as

AnimalsMembrane ProteinsPhotoreceptor Cells, InvertebrateXenopus laevisMembrane Proteins

Identifiers

PMID31594805
PMCPMC6829649
OpenAlexW2979929622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.