Evidence map›Paper›PMID 31594770›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2019

The value of the GP's clinical judgement in predicting dementia: a multicentre prospective cohort study among patients in general practice.

Michael Pentzek, Michael Wagner, Heinz-Harald Abholz, Horst Bickel, Hanna Kaduszkiewicz, Birgitt Wiese, Siegfried Weyerer, Hans-Helmut König, Martin Scherer, Steffi G Riedel-Heller and 3 more

Abstract readMulticenter Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Brain sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael PentzekInstitute of General Practice (ifam), Medical Faculty, University of Düsseldorf, Düsseldorf.
Michael WagnerDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn.
Heinz-Harald AbholzInstitute of General Practice (ifam), Medical Faculty, University of Düsseldorf, Düsseldorf.
Horst BickelDepartment of Psychiatry, Technical University of Munich, Munich.
Hanna KaduszkiewiczInstitute of General Practice, Medical Faculty, Kiel University, Kiel.
Birgitt WieseInstitute for General Practice, Hannover Medical School, Hannover.
Siegfried WeyererCentral Institute of Mental Health, Medical Faculty, Mannheim/Heidelberg University, Mannheim.
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics.
Martin SchererDepartment of Primary Medical Care, University Medical Center Hamburg-Eppendorf, Hamburg.
Steffi G Riedel-HellerInstitute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig.
Wolfgang MaierDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn; German Center for Neurodegenerative Diseases (DZNE), Bonn.
Alexander KopparaDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn; German Center for Neurodegenerative Diseases (DZNE), Bonn.
AgeCoDe Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical judgement is intrinsic to diagnostic strategies in general practice; however, empirical evidence for its validity is sparse.

aimTo ascertain whether a GP's global clinical judgement of future cognitive status has an added value for predicting a patient's likelihood of experiencing dementia. DESIGN AND

settingMulticentre prospective cohort study among patients in German general practice that took place from January 2003 to October 2016.

methodPatients without baseline dementia were assessed with neuropsychological interviews over 12 years; 138 GPs rated the future cognitive decline of their participating patients. Associations of baseline predictors with follow-up incident dementia were analysed with mixed-effects logistic and Cox regression.

resultsA total of 3201 patients were analysed over the study period (mean age = 79.6 years, 65.3% females, 6.7% incident dementia in 3 years, 22.1% incident dementia in 12 years). Descriptive analyses and comparison with other cohorts identified the participants as having frequent and long-lasting doctor-patient relationships and being well known to their GPs. The GP baseline rating of future cognitive decline had significant value for 3-year dementia prediction, independent of cognitive test scores and patient's memory complaints (GP ratings of very mild (odds ratio [OR] 1.97, 95% confidence intervals [95% CI] = 1.28 to 3.04); mild (OR 3.00, 95% CI = 1.90 to 4.76); and moderate/severe decline (OR 5.66, 95% CI = 3.29 to 9.73)). GPs' baseline judgements were significantly associated with patients' 12-year dementia-free survival rates (Mantel-Cox log rank test

conclusionIn this sample of patients in familiar doctor-patient relationships, the GP's clinical judgement holds additional value for predicting dementia, complementing test performance and patients' self-reports. Existing and emerging primary care-based dementia risk models should consider the GP's judgement as one predictor. Results underline the importance of the GP-patient relationship.

Indexed as

Clinical Decision-MakingEvidence-Based PracticeGeneral PracticeAgedDementiaFemaleGeneral PractitionersGermanyHumansJudgmentMalePhysician-Patient RelationsProspective StudiesReferral and Consultationclinical decision makingcognitive declinedementiageneral practiceintuitionvalidity

Identifiers

PMID31594770
PMCPMC6783138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.