Evidence map›Paper›PMID 31594539›Full record

ArticleAIDS research and therapy2019

Predictors of loss to follow-up in art experienced patients in Nigeria: a 13 year review (2004-2017).

Ahmad Aliyu, Babatunde Adelekan, Nifarta Andrew, Eunice Ekong, Stephen Dapiap, Fati Murtala-Ibrahim, Iboro Nta, Nicaise Ndembi, Charles Mensah, Patrick Dakum

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Article in AIDS research and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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24citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ahmad AliyuInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Babatunde AdelekanInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria. babalekan2000@yahoo.com.
Nifarta AndrewInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Eunice EkongInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Stephen DapiapInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Fati Murtala-IbrahimInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Iboro NtaInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Nicaise NdembiInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Charles MensahInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.
Patrick DakumInstitute of Human Virology Nigeria (IHVN), Abuja, Nigeria.

Funding

PEPFAR
6 · The paper itself

Abstract

backgroundExpanded access to antiretroviral therapy (ART) leads to improved HIV/AIDS treatment outcomes in Nigeria, however, increasing rates of loss to follow-up among those on ART is threatening optimal standard achievement. Therefore, this retrospective cross-sectional study is aimed at identifying correlates and predictors of loss to follow-up in patients commencing ART in a large HIV program in Nigeria.

methodsRecords of all patients from 432 US CDC Presidents Emergency Plan for AIDS Relief (PEPFAR) supported facilities across 10 States and FCT who started ART from 2004 to 2017 were used for this study. Bivariate and multivariate analysis of the demographic and clinical parameters of all patients was conducted using STATA version 14 to determine correlates and predictors of loss to follow-up.

resultsWithin the review period, 245,257 patients were ever enrolled on anti-retroviral therapy. 150,191 (61.2%) remained on treatment, 10,960 (4.5%) were transferred out to other facilities, 6926 (2.8%) died, 2139 (0.9%) self-terminated treatment and 75,041 (30.6%) had a loss to follow-up event captured. Males (OR: 1.16), Non-pregnant female (OR: 4.55), Patients on ≥ 3-monthly ARV refills (OR: 1.32), Patients with un-suppressed viral loads on ART (OR: 4.52), patients on adult 2nd line regimen (OR: 1.23) or pediatric on 1st line regimen (OR: 1.70) were significantly more likely to be lost to follow-up.

conclusionDespite increasing access to anti-retroviral therapy, loss to follow-up is still a challenge in the HIV program in Nigeria. Differentiated care approaches that will focus on males, non-pregnant females and paediatrics is encouraged. Reducing months of Anti-retroviral drug refill to less than 3 months is advocated for increased patient adherence.

Indexed as

Lost to Follow-UpProgram EvaluationAdolescentAdultAgedAnti-Retroviral AgentsChildChild, PreschoolCross-Sectional StudiesFemaleFollow-Up StudiesHIV InfectionsHumansInfantMaleMiddle AgedAnti-Retroviral AgentsARTLoss to follow-upNigeria

Identifiers

PMID31594539
PMCPMC6784330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.