ArticleProceedings. Biological sciences2019
Phylodynamics reveals extinction-recolonization dynamics underpin apparently endemic vampire bat rabies in Costa Rica.
Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Spatio-temporal dynamics of Hendra virus in Australia reveal stable maintenance of diverse viral clades among Pteropus bats.Nature microbiology · 2026Article
- Bat things come in threes: within-host dynamics of herpesvirus triple infection in bats.Journal of virology · 2025Article
- Drivers of rabies virus spillover risk from vampire bats to livestock in Colombia.PLoS neglected tropical diseases · 2025Article
- Role of individual and population heterogeneity in shaping dynamics of multi-pathogen shedding in an island endemic bat.PLoS pathogens · 2025Article
- Anticoagulants for the Control of the Common Vampire Bat (Desmodus rotundus).Zoonoses and public health · 2025Review
- Rabies transmitted from vampires to cattle: An overview.PloS one · 2025Article
- Bat Rabies in the Americas: IsViruses · 2024Article
- Advances in understanding bat infection dynamics across biological scales.Proceedings. Biological sciences · 2024Review
- Inferring the disruption of rabies circulation in vampire bat populations using a betaherpesvirus-vectored transmissible vaccine.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Ecological determinants of rabies virus dynamics in vampire bats and spillover to livestock.Proceedings. Biological sciences · 2022Article
- Geographic Distribution of Common Vampire BatPathogens (Basel, Switzerland) · 2022Article
- Longitudinal deep sequencing informs vector selection and future deployment strategies for transmissible vaccines.PLoS biology · 2022Article
- On the Use of Phylogeographic Inference to Infer the Dispersal History of Rabies Virus: A Review Study.Viruses · 2021Review
- Rabies in Costa Rica - Next Steps Towards Controlling Bat-Borne Rabies After its Elimination in Dogs.The Yale journal of biology and medicine · 2021Review
- Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats.Viruses · 2021Article
- Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations.Nature communications · 2020Article
- Review
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
Variation in disease incidence in wildlife is often assumed to reflect environmental or demographic changes acting on an endemic pathogen. However, apparent endemicity might instead arise from spatial processes that are challenging to identify from traditional data sources including time series and field studies. Here, we analysed longitudinal sequence data collected from rabies virus outbreaks over 14 years in Costa Rica, a Central American country that has recorded continuous vampire bat-transmitted rabies outbreaks in humans and livestock since 1985. We identified five phylogenetically distinct lineages which shared most recent common ancestors with viruses from North and South America. Bayesian phylogeographic reconstructions supported bidirectional viral dispersals involving countries to the north and south of Costa Rica at different time points. Within Costa Rica, viruses showed little contemporaneous spatial overlap and no lineage was detected across all years of surveillance. Statistical models suggested that lineage disappearances were more likely to be explained by viral extinctions than undetected viral circulation. Our results highlight the importance of international viral dispersal for shaping the burden of rabies in Costa Rica, suggest a Central American corridor of rabies virus invasions between continents, and show that apparent disease endemicity may arise through recurrent pathogen extinctions and reinvasions which can be readily detected in relatively small datasets by joining phylodynamic and modelling approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.