Evidence map›Paper›PMID 31594227›Full record

ArticleJournal of Alzheimer's disease : JAD2019

Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data.

Harriet J Forbes, Angel Y S Wong, Caroline Morton, Krishnan Bhaskaran, Liam Smeeth, Marcus Richards, Sigrun A J Schmidt, Sinéad M Langan, Charlotte Warren-Gash

Open access · hybridAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Life Events and Incident Dementia: A Prospective Study of 493,787 Individuals Over 16 Years.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Harriet J ForbesLondon School of Hygiene & Tropical Medicine, London, UK.
Angel Y S WongLondon School of Hygiene & Tropical Medicine, London, UK.
Caroline MortonLondon School of Hygiene & Tropical Medicine, London, UK.
Krishnan BhaskaranLondon School of Hygiene & Tropical Medicine, London, UK.
Liam SmeethLondon School of Hygiene & Tropical Medicine, London, UK.
Marcus RichardsMRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.
Sigrun A J SchmidtDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Sinéad M LanganLondon School of Hygiene & Tropical Medicine, London, UK.
Charlotte Warren-GashLondon School of Hygiene & Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBAarhus University Hospital · DKMRC Unit for Lifelong Health and Ageing · GB

Funding

Department of Health NIHR/CS/010/014Medical Research Council MC_UU_00019/3Medical Research Council MC_UU_12019/3Medical Research Council MR/S003940/1Wellcome Trust 201440/Z/16/ZWellcome Trust 205039/Z/16/Z
6 · The paper itself

Abstract

backgroundIn the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care.

objectiveThis study aimed to investigate if bereavement influenced the probability of having received a dementia diagnosis.

methodsA population-based cohort study using UK electronic health records, between 1997 and 2017, among 247,586 opposite-sex partners. Those experiencing partner bereavement were matched (age, sex, and date of bereavement) to a non-bereaved person living in a partnership. Multivariate cox regression was performed.

resultsPartner bereavement was associated with an increased risk of receiving a diagnosis of dementia in the first three months (hazard ratio (HR) 1.43, 95% CI 1.20-1.71) and first six months (HR 1.24, 95% CI 1.09-1.41), while there was a small reduced risk of getting a dementia diagnosis over all follow-up (HR 0.94, 95% CI 0.89-0.98).

conclusionsPartner bereavement appears to lead to a short-term increased risk of the surviving partner receiving a diagnosis of dementia, suggesting that bereavement unmasks existing undiagnosed dementia. Over the longer term, however, bereaved individuals are less likely to have a diagnosis of dementia in their health records than non-bereaved individuals.

Indexed as

BereavementAdultAgedAged, 80 and overCohort StudiesDementiaFemaleHealth StatusHumansMaleMiddle AgedRisk FactorsUnited KingdomBereavementClinical Practice Research Datalinkdementiadiagnosisepidemiology

Identifiers

PMID31594227
PMCPMC6918907
OpenAlexW2979057575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.