Evidence map›Paper›PMID 31593482›Full record

ArticleThe British journal of radiology2019

PET imaging of a

Yuping Xu, Lizhen Wang, Donghui Pan, Chunjing Yu, Baoming Mi, Qianhuan Huang, Jie Sheng, Junjie Yan, Xinyu Wang, Runlin Yang and 1 more

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. The diagnostic value ofFrontiers in medicine · 2024
    Article
  10. Preclinical evaluation ofEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  11. Review
  12. Phase I clinical evaluation ofTheranostics · 2023
    Article
  13. Article
  14. Review
  15. Application of a NovelFrontiers in oncology · 2022
    Article
  16. PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology.International journal of molecular sciences · 2021
    Review
  17. [Molecules (Basel, Switzerland) · 2021
    Article
  18. Impact ofEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
  19. Synthesis of a novelEJNMMI research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yuping XuKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Lizhen WangKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Donghui PanKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Chunjing YuDepartment of Nuclear Medicine, Affiliated Hospital of Jiangnan University, Wuxi No. 4 People's Hospital, Wuxi, 214062, China.
Baoming MiDepartment of Nuclear Medicine, Affiliated Hospital of Jiangnan University, Wuxi No. 4 People's Hospital, Wuxi, 214062, China.
Qianhuan HuangDepartment of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 210029, China.
Jie ShengDepartment of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 210029, China.
Junjie YanKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Xinyu WangKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Runlin YangKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Min YangKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.
Ministry Of Health · FJNanjing Medical University · CNWuxi No.2 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOverexpression of human epidermal growth factor receptor-2 (HER2) in breast cancers provides promising opportunities for imaging and targeted therapy. Developing HER2 targeted positron emission tomography (PET) probes might be benefit for management of the disease. Small high-affinity scaffold proteins, affibodies, are ideal vectors for imaging HER2 overexpressed tumors. Despite of the initial success on development of

methodsNOTA-MAL conjugated Cys-MZHER

resultsThe tracer was synthesized in a straightforward chelation method with satisfactory non-decay corrected yield (81±5%) and radiochemical purity (>95%).

conclusionIn summary, this study indicates the significant efficiency of the ADVANCES IN KNOWLEDGE: The research investigated the feasibility of a

Indexed as

AnimalsBreast NeoplasmsChromatography, High Pressure LiquidErb-b2 Receptor Tyrosine KinasesFeasibility StudiesFemaleGallium RadioisotopesHeterograftsHumansKidneyMCF-7 CellsMiceMice, NudePositron-Emission TomographyPositron Emission Tomography Computed TomographyRecombinant Fusion Proteinsaffibody (ZHER2-342)2ERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesGallium RadioisotopesRecombinant Fusion Proteins

Identifiers

PMID31593482
PMCPMC6913365
OpenAlexW2979675991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.