ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020
Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- The Baeyer-Villiger Oxidation of Cubyl Ketones: A Synthetic Route to Functionalized Cubanols.Organic letters · 2025Article
- Highly-Selective Electrochemical Decarboxylative Late-Stage Functionalization of Amino Acids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Entry to 2-aminoprolines via electrochemical decarboxylative amidation ofBeilstein journal of organic chemistry · 2025Article
- Continuous flow synthesis enabling reaction discovery.Chemical science · 2024Review
- Taking electrodecarboxylative etherification beyond Hofer-Moest using a radical C-O coupling strategy.Nature communications · 2020Article
- Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The highly strained cubane system is of great interest as a scaffold and rigid linker in both pharmaceutical and materials chemistry. The first electrochemical functionalisation of cubane by oxidative decarboxylative ether formation (Hofer-Moest reaction) was demonstrated. The mild conditions are compatible with the presence of other oxidisable functional groups, and the use of flow electrochemical conditions allows straightforward upscaling.
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Registered trials
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