Evidence map›Paper›PMID 31593200›Full record

ArticleChemical communications (Cambridge, England)2019

High affinity threading of a new tetralactam macrocycle in water by fluorescent deep-red and near-infrared squaraine dyes.

Janel M Dempsey, Canjia Zhai, Hannah H McGarraugh, Cynthia L Schreiber, Shannon E Stoffel, Andrew Johnson, Bradley D Smith

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Partially Sulfated Pillar[5]Arenes: Synthesis and Molecular Recognition Properties.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. In Vitro and In Vivo Sequestration of Phencyclidine by MeChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  8. Article
  9. Pillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water.Angewandte Chemie (International ed. in English) · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Janel M DempseyDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0001-8850-7292
Canjia ZhaiDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.
Hannah H McGarraughDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0001-8003-040X
Cynthia L SchreiberDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.
Shannon E StoffelDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.
Andrew JohnsonDivision of Science, Lindsey Wilson College, 317 Fugitte Science Center, Columbia, KY 42728, USA.
Bradley D SmithDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Nieuwland Science Hall, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0003-4120-3210

Funding

PROMOTERS AND INHIBITORS OF MEMBRANE FUSIONR01GM059078 · NIGMS · UNIVERSITY OF NOTRE DAME · PI SMITH, BRADLEY D · 1999 to 2019
$5.8M
NIGMS NIH HHS R01 GM059078
6 · The paper itself

Abstract

A new tetralactam macrocycle was prepared and found to encapsulate deep-red and near-infrared squaraine and croconaine dyes in water with tunable threading kinetics. The new supramolecular paradigm of guest back-folding was used to increase macrocycle/squaraine affinity by 370-fold and achieve an association constant of 2.8 × 10

Identifiers

PMID31593200
PMCPMC6827183

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.