ReviewTopics in magnetic resonance imaging : TMRI2019
Placental MRI: Developing Accurate Quantitative Measures of Oxygenation.
Review in Topics in magnetic resonance imaging : TMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Placental MRI texture features in prenatal exposure to opioids and tobacco.Scientific reports · 2025Article
- Comparative efficacy of MRI versus ultrasound in prenatal diagnosis of placenta accreta spectrum disorders: a single-tertiary center study.Archives of gynecology and obstetrics · 2025Article
- Heme oxygenase/carbon monoxide system affects the placenta and preeclampsia.Medical gas research · 2025Review
- Feasibility of multimodal magnetic resonance imaging to assess maternal hyperoxygenation in sheep pregnancy.The Journal of physiology · 2025Article
- Use of Photoacoustic Imaging to Study the Effects of Anemia on Placental Oxygen Saturation in Normoxic and Hypoxic Conditions.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- AnyStar: Domain randomized universal star-convex 3D instance segmentation.IEEE Winter Conference on Applications of Computer Vision. IEEE Winter Conference on Applications of Computer Vision · 2024Article
- Advanced magnetic resonance imaging in human placenta: insights into fetal growth restriction and congenital heart disease.Frontiers in cardiovascular medicine · 2024Review
- Shape-aware Segmentation of the Placenta in BOLD Fetal MRI Time Series.The journal of machine learning for biomedical imaging · 2023Article
- A review of feto-placental vasculature flow modelling.Placenta · 2023Review
- The human placenta project: Funded studies, imaging technologies, and future directions.Placenta · 2023Review
- Assessing within-subject rates of change of placental MRI diffusion metrics in normal pregnancy.Magnetic resonance in medicine · 2023Article
- Cerebral oxygen metabolism from MRI susceptibility.NeuroImage · 2023Review
- Improving Development of Drug Treatments for Pregnant Women and the Fetus.Therapeutic innovation & regulatory science · 2022Review
- Volumetric Parameterization of the Placenta to a Flattened Template.IEEE transactions on medical imaging · 2022Article
- Fetal Neuroimaging Updates.Magnetic resonance imaging clinics of North America · 2021Review
- Placental MRI: Effect of maternal position and uterine contractions on placental BOLD MRI measurements.Placenta · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
Abstract
The Human Placenta Project has focused attention on the need for noninvasive magnetic resonance imaging (MRI)-based techniques to diagnose and monitor placental function throughout pregnancy. The hope is that the management of placenta-related pathologies would be improved if physicians had more direct, real-time measures of placental health to guide clinical decision making. As oxygen alters signal intensity on MRI and oxygen transport is a key function of the placenta, many of the MRI methods under development are focused on quantifying oxygen transport or oxygen content of the placenta. For example, measurements from blood oxygen level-dependent imaging of the placenta during maternal hyperoxia correspond to outcomes in twin pregnancies, suggesting that some aspects of placental oxygen transport can be monitored by MRI. Additional methods are being developed to accurately quantify baseline placental oxygenation by MRI relaxometry. However, direct validation of placental MRI methods is challenging and therefore animal studies and ex vivo studies of human placentas are needed. Here we provide an overview of the current state of the art of oxygen transport and quantification with MRI. We suggest that as these techniques are being developed, increased focus be placed on ensuring they are robust and reliable across individuals and standardized to enable predictive diagnostic models to be generated from the data. The field is still several years away from establishing the clinical benefit of monitoring placental function in real time with MRI, but the promise of individual personalized diagnosis and monitoring of placental disease in real time continues to motivate this effort.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.