Evidence map›Paper›PMID 31592936›Full record

ArticlePsychosomatic medicine2020

Linking Daily-Life Interpersonal Stressors and Health Problems Via Affective Reactivity in Borderline Personality and Depressive Disorders.

Johanna Hepp, Sean P Lane, Ryan W Carpenter, Timothy J Trull

Open access · greenAbstract read
In one paragraph

Article in Psychosomatic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Johanna HeppFrom the Department of Psychosomatic Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University (Hepp), Mannheim, Germany; Department of Psychological Sciences (Lane), Purdue University, West Lafayette, Indiana; Center for Alcohol and Addiction Studies, Brown University (Carpenter), Providence, Rhode Island; and Department of Psychological Sciences, University of Missouri (Trull), Columbia, Missouri.
Sean P Lane
Ryan W Carpenter
Timothy J Trull
Central Institute of Mental Health · DEBrown University · USHeidelberg University · DE

Funding

ALCOHOL INTERVENTION/TREATMENT OUTCOME RESEARCH TRAININGT32AA007459 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA, PETER M. MONTI · 1986 to 2026
$13.3M
Psychology of Alcohol Use and Dependence TrainingT32AA013526 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI DENIS M MCCARTHY, KENNETH JAMES SHER · 2002 to 2026
$9.0M
Resource CoreP60AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI MADDEN, PAMELA ANN · 2009 to 2013
$8.8M
Toward a Generalized Framework and Flexible Software Environment for Power Analysis of Alcohol Treatment Randomized Controlled TrialsR01AA027264 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI HENNES, ERIN, LANE, SEAN P · 2018 to 2022
$3.4M
Characterizing Affective Instability Using EMAR21MH069472 · NIMH · UNIVERSITY OF MISSOURI-COLUMBIA · PI TRULL, TIMOTHY J · 2004 to 2006
$539k
NIAAA NIH HHS P60 AA011998NIAAA NIH HHS R01 AA027264NIAAA NIH HHS T32 AA007459NIAAA NIH HHS T32 AA013526NIMH NIH HHS R21 MH069472
6 · The paper itself

Abstract

objectiveBorderline personality disorder (BPD) is associated with unstable interpersonal relationships, affective instability, and physical health problems. In individuals with BPD, intense affective reactions to interpersonal stressors may contribute to the increased prevalence of health problems.

methodsBPD (n = 81) and depressed participants (DD; n = 50) completed six daily ambulatory assessment prompts for 28 days. At each prompt, participants reported interpersonal stressors (disagreements, rejections, feeling let down), negative affect, and health problems in four domains (gastrointestinal, respiratory, aches, depressive symptoms). In multilevel moderated mediation models, we examined the indirect effects of interpersonal stressors on health problems via negative affect, by group.

resultsInterpersonal stressors were positively associated with negative affect in both groups (β values > 0.12, p values < .001), but more so for participants with BPD (βDay = 0.05, p < .001). Negative affect was positively associated with health problems across all domains (βMoment/Day values > 0.01, p values < .046), but associations were larger at the day level for respiratory symptoms in BPD (β = 0.02, p = .025) and for depressive symptoms in DD (β = 0.04, p < .001). Negative affect mediated the association of interpersonal stressors and health problems in both groups, with larger effects for the DD group for depressive problems (β = 0.02, p = .092) and for the BPD group for the other three domains (β values > 0.02, p values < .090).

conclusionsInterpersonal stressors may contribute to increased physical health problems via an inability to regulate affective responses to such events. This pathway may be stronger in several health domains for those with BPD and may contribute to an elevated risk of morbidity and mortality in this disorder, suggesting a target for intervention to reduce these risks.

Indexed as

Health StatusInterpersonal RelationsAdolescentAdultAffectAgedBorderline Personality DisorderDepressive DisorderEcological Momentary AssessmentEmotional RegulationFemaleHumansMaleMiddle AgedModels, StatisticalStress, Psychological

Identifiers

PMID31592936
PMCPMC6934909
OpenAlexW2979591843

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.