Evidence map›Paper›PMID 31592508›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2019

Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities.

Taylor D Ottesen, Alp Yurter, Blake N Shultz, Anoop R Galivanche, Cheryl K Zogg, Patawut Bovonratwet, Lee E Rubin, Jonathan N Grauer

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Taylor D OttesenDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Alp YurterDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Blake N ShultzDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Anoop R GalivancheDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Cheryl K ZoggDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Patawut BovonratwetDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Lee E RubinDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Jonathan N GrauerDepartment of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT.
Yale University · USKonrad-Adenauer-Stiftung · DE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
NCATS NIH HHS UL1 TR001863NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

Previous studies evaluating the risk of perioperative adverse events after hip fracture surgery for dialysis-dependent patients are either institutional cohort studies or limited by patient numbers. The current study uses the National Surgical Quality Improvement Program database's large national patient population and 30-day follow-up window to address these weaknesses.

methodsNational Surgical Quality Improvement Program databases (2006 to 2016) were queried for patients aged 60 years or older who underwent hip fracture surgery. Differences in 30-day outcomes based on preoperative dialysis dependence were compared using risk-adjusted logistic regression and coarsened exact matching for adverse events, need for revision surgery, readmission, and mortality. The proportion of adverse events that occurred before versus after discharge was also assessed.

resultsA total of 288 dialysis-dependent and 16,392 non-dialysis-dependent patients met the inclusion criteria. Matched populations controlling for demographic factors (ie, age, sex, body mass index, and functional status) and overall health (American Society of Anesthesiologists class) found dialysis-dependent patients to be associated with significantly greater odds of any adverse event (odds ratio [OR] = 1.90), major adverse event (OR = 1.77), and unplanned readmission (OR = 2.48). Increased odds of minor adverse event (OR = 1.05), return to the operating room (OR = 1.66), and death (OR = 1.42) within 30 postoperative days were also found but were not statistically significant. DISCUSSION: Even after controlling for demographics and health status, geriatric dialysis patients undergoing surgery for hip fracture are at significantly greater odds of adverse outcomes. Because of increased risks for geriatric dialysis patients undergoing surgery for hip fracture, surgical caution, patient counseling, and heightened surveillance must be observed throughout the perioperative period for this fragile population. Furthermore, hospitals and physicians must take the increased risks associated with dialysis into account when considering bundled payment reimbursement strategies and resource allocation for hip fracture care.

Identifiers

PMID31592508
PMCPMC6754213
OpenAlexW2967583452

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.