ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019
Endoscopically Injectable Shear-Thinning Hydrogels Facilitating Polyp Removal.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Sodium Alginate-Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection.Advanced healthcare materials · 2026Article
- Functional hydrogels as submucosal injectable materials in therapeutic endoscopy.Biomedical engineering letters · 2026Review
- Hydrogel adhesives for upper gastrointestinal wound healing.Theranostics · 2026Review
- Enhancing remanent magnetization of injectable hydrogels improves realtime transluminal localization of tumor in hollow soft viscera.Bioactive materials · 2026Article
- In Situ Photoactivated Hydrogel Adhesive Dressings for Post Colon Polypectomies (PolypCures).bioRxiv : the preprint server for biology · 2025Article
- Review of the role of submucosal injection materials in digestive endoscopy.Annals of medicine · 2025Review
- Sequential drug release system: Targeting the tumor ECM for enhanced chemotherapy efficacy.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Hybrid Nanoparticle-Hydrogel Systems for Drug Delivery Depots and Other Biomedical Applications.ACS nano · 2024Review
- Synergistic Drug-Loaded Shear-Thinning Star Polymer Hydrogel Facilitates Gastrointestinal Lesion Resection and Promotes Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- LaponiteMolecules (Basel, Switzerland) · 2024Review
- Injectable temperature-sensitive hydrogel facilitating endoscopic submucosal dissection.Frontiers in bioengineering and biotechnology · 2024Article
- Multifunctional two-component in-situ hydrogel for esophageal submucosal dissection for mucosa uplift, postoperative wound closure and rapid healing.Bioactive materials · 2023Article
- Endoscopically injectable and self-crosslinkable hydrogel-mediated stem cell transplantation for alleviating esophageal stricture after endoscopic submucosal dissection.Bioengineering & translational medicine · 2023Article
- A shear-thinning, ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis.Bioactive materials · 2023Article
- A review of hydrogels used in endoscopic submucosal dissection for intraoperative submucosal cushions and postoperative management.Regenerative biomaterials · 2023Review
- Stem cell-laden hydrogel bioink for generation of high resolution and fidelity engineered tissues with complex geometries.Bioactive materials · 2022Article
- Easily-injectable shear-thinning hydrogel provides long-lasting submucosal barrier for gastrointestinal endoscopic surgery.Bioactive materials · 2022Article
- Foundations of gastrointestinal-based drug delivery and future developments.Nature reviews. Gastroenterology & hepatology · 2022Review
- Influence of the Mixtures of Vegetable Oil and Vitamin E over the Microstructure and Rheology of Organogels.Gels (Basel, Switzerland) · 2022Article
- A microexplosive shockwave-based drug delivery microsystem for treating hard-to-reach areas in the human body.Microsystems & nanoengineering · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Submucosal elevation, the process of instilling material in the submucosal space for separation of the surface mucosa and deeper muscularis layer, is a significant aspect of the endoscopic mucosal resection of large lesions performed to facilitate lesion removal and maximize safety. Submucosal injection, when applied, has historically been performed with normal saline, though this is limited by its rapid dissipation; solutions ideally need to be easily injectable, biocompatible, and provide a long-lasting submucosal cushion with a desirable height. Here, reported is a new set of materials, endoscopically injectable shear-thinning hydrogels, meeting these requirements because of their biocompatible components and ability to form a solid hydrogel upon injection. These findings are supported by evaluation in a large animal model and ultimately demonstrate the potential of these shear-thinning hydrogels to serve as efficient submucosal injection fluids for cushion development. Given these unique characteristics, their broad application in mucosal resection techniques is anticipated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.