Evidence map›Paper›PMID 31592410›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019

Therapeutic Targeting of

Erhu Fang, Xiaojing Wang, Feng Yang, Anpei Hu, Jianqun Wang, Dan Li, Huajie Song, Mei Hong, Yanhua Guo, Yang Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. MZF1-AS1/NSUN2 promotes the peritoneal metastasis of gastric cancer by enhancing the stability of RAB13 mRNA.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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  9. Targeting the glutamine-arginine-proline metabolism axis in cancer.Journal of enzyme inhibition and medicinal chemistry · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Erhu FangDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Xiaojing WangClinical Center of Human Genomic Research Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Feng YangDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Anpei HuDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Jianqun WangDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Dan LiDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Huajie SongDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Mei HongDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Yanhua GuoDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Yang LiuDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Hongjun LiDepartment of Pathology Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Kai HuangClinical Center of Human Genomic Research Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Liduan ZhengClinical Center of Human Genomic Research Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.
Qiangsong TongDepartment of Pediatric Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 Hubei Province P. R. China.ORCID https://orcid.org/0000-0002-2615-6404
Wuhan Union Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proline synthesis plays an important role in the metabolic reprogramming that contributes to tumor progression. However, the mechanisms regulating expression of proline synthetic genes in neuroblastoma (NB) remain elusive. Herein, through integrative screening of a public dataset and amino acid profiling analysis, myeloid zinc finger 1 (

Indexed as

E2F transcription factor 1myeloid zinc finger 1 antisense RNA 1poly(ADP‐ribose) polymerase 1proline synthesistumor progression

Identifiers

PMID31592410
PMCPMC6774027
OpenAlexW2967693430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.