Evidence map›Paper›PMID 31592303›Full record

ArticleBiomicrofluidics2019

A numerical study of the selectivity of an isolated cylindrical or conical nanopore to a charged macro-ion.

Doyel Pandey, Somnath Bhattacharyya, Sandip Ghosal

Abstract read
In one paragraph

Article in Biomicrofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Doyel PandeyDepartment of Mathematics, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Somnath BhattacharyyaDepartment of Mathematics, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.ORCID 0000-0002-0730-4934
Sandip GhosalDepartment of Mechanical Engineering and Engineering Sciences and Applied Mathematics, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.ORCID 0000-0001-6587-3716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selectivity of a single nanopore in a uniformly charged solid membrane to a charged analyte ion is studied using numerical simulation. A continuum model is used where the ions are regarded as point particles and characterized by a continuously varying number density. The problem is described by the coupled equations for the electrostatic potential, ion-transport, and hydrodynamic flow, which are solved under appropriate boundary conditions using a finite volume method. The nanopore geometry is considered conical, the cylindrical pore being a special case where the cone angle is zero. The selectivity is characterized by a dimensionless parameter: the pore selectivity index. Results are presented showing how the pore selectivity index varies with the membrane surface charge and other parameters of the problem. The role of hydrodynamic flow on transport properties is examined and found to be consistent with theoretical results on electroosmotic flow through nanopores.

Identifiers

PMID31592303
PMCPMC6773593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.