Evidence map›Paper›PMID 31592163›Full record

ArticleACS omega2019

Discovery of Ligand-Efficient Scaffolds for the Design of Novel

Shannon Auletta, Wagma Caravan, Julia K Persaud, Samantha F Thuilot, Dean G Brown, David W Parkin, Brian J Stockman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Analytical chemistry · 2026
    Article
  2. Article
  3. RSC chemical biology · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shannon AulettaDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Wagma CaravanDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Julia K PersaudDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Samantha F ThuilotDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Dean G BrownHit Discovery, Discovery Sciences, IMED Biotech Unit, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.
David W ParkinDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Brian J StockmanDepartment of Chemistry, Adelphi University, 1 South Avenue, Garden City, New York 11530, Unites States.
Adelphi University · USAstraZeneca (United States) · US

Funding

Nucleoside ribohydrolases as targets for Trichomonas vaginalis therapeutic agents. This project will evaluate two essential nucleoside ribohydrolase enzymes as targets for novel antitrichomonal drugs.R15AI128585 · NIAID · ADELPHI UNIVERSITY · PI STOCKMAN, BRIAN J · 2017 to 2017
$311k
NIAID NIH HHS R15 AI128585
6 · The paper itself

Abstract

Trichomoniasis is caused by the parasitic protozoan

Identifiers

PMID31592163
PMCPMC6777076
OpenAlexW2974828344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.