Evidence map›Paper›PMID 31592124›Full record

ArticleInternational journal of biological sciences2019

Ciliary IFT80 regulates dental pulp stem cells differentiation by FGF/FGFR1 and Hh/BMP2 signaling.

Xue Yuan, Min Liu, Xu Cao, Shuying Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Role of Primary Cilia in Bone and Cartilage.Journal of dental research · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xue YuanDepartment of Oral Biology, School of Dental Medicine, University of Buffalo, State University of New York, Buffalo, NY, United States.
Min LiuDepartment of Anatomy & Cell Biology, School of Dental Medicine, University of Pennsylvania, PA, United States.
Xu CaoDepartment of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Shuying YangDepartment of Oral Biology, School of Dental Medicine, University of Buffalo, State University of New York, Buffalo, NY, United States.
University at Buffalo, State University of New York · USJohns Hopkins University · USUniversity of Pennsylvania · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Regulation of skeletal development and homeostasis by IFT proteinR01DE023105 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI YANG, SHUYING · 2014 to 2018
$2.0M
Role of RGS12, a Regulator of G protein Signaling, in Bone RemodelingR01AR066101 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI YANG, SHUYING · 2014 to 2018
$1.8M
Function of Regulator of G protein signaling in aging skeletonR01AG048388 · NIA · UNIVERSITY OF PENNSYLVANIA · PI YANG, SHUYING · 2014 to 2018
$1.7M
NCI NIH HHS P30 CA016056NIAMS NIH HHS R01 AR066101NIA NIH HHS R01 AG048388NIDCR NIH HHS R01 DE023105
6 · The paper itself

Abstract

Primary cilia and intraflagellar transport (IFT) proteins control a wide variety of processes during development and tissue homeostasis. However, their potential roles in the regulation of stem cell differentiation and tooth development remain elusive. Here, we uncovered the critical roles of ciliary IFT80 in cilia formation and differentiation of dental pulp stem cells (DPSCs).

Indexed as

AnimalsBone Morphogenetic Protein 2Cell DifferentiationCiliaDental PulpFibroblast Growth FactorsHumansImmunohistochemistryMiceReceptor, Fibroblast Growth Factor, Type 1Signal TransductionStem CellsBone Morphogenetic Protein 2Fibroblast Growth FactorsReceptor, Fibroblast Growth Factor, Type 1bone morphogenetic proteindental pulp stem cellsfibroblast growth factor signalinghedgehog signalingintraflagellar transportPrimary cilia

Identifiers

PMID31592124
PMCPMC6775288
OpenAlexW2967103203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.