Evidence map›Paper›PMID 31592020›Full record

ReviewFrontiers in genetics2019

Mathematical Models of Organoid Cultures.

Sandra Montes-Olivas, Lucia Marucci, Martin Homer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Tumor organoids modeling reveals timed responses and interplay of radiotherapy and chemotherapy in pancreatic cancer.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Frontiers in bioengineering and biotechnology · 2024
    Review
  10. Generative models of morphogenesis in developmental biology.Seminars in cell & developmental biology · 2023
    Review
  11. Article
  12. Review
  13. Review
  14. Systems bioengineering approaches for developmental toxicology.Computational and structural biotechnology journal · 2023
    Review
  15. Review
  16. Organoids as complex (bio)systems.Frontiers in cell and developmental biology · 2023
    Review
  17. Organoid Cultures In Silico: Tools or Toys?Bioengineering (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sandra Montes-OlivasDepartment of Engineering Mathematics, University of Bristol, Bristol, United Kingdom.
Lucia MarucciDepartment of Engineering Mathematics, University of Bristol, Bristol, United Kingdom.
Martin HomerDepartment of Engineering Mathematics, University of Bristol, Bristol, United Kingdom.
University of Bristol · GB

Funding

Medical Research Council MR/N021444/1
6 · The paper itself

Abstract

Organoids are engineered three-dimensional tissue cultures derived from stem cells and capable of self-renewal and self-organization into a variety of progenitors and differentiated cell types. An organoid resembles the cellular structure of an organ and retains some of its functionality, while still being amenable to

Indexed as

3D tissueagent-based modelscomputational modelingdifferential equationsmathematical modelingorganoids

Identifiers

PMID31592020
PMCPMC6761251
OpenAlexW2969249809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.