Evidence map›Paper›PMID 31591838›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2019

Elevated Serum Uric Acid in Benign Convulsions with Mild Gastroenteritis in Children.

Il Han Yoo, Woojoong Kim, Jaeso Cho, Hunmin Kim, Byung Chan Lim, Hee Hwang, Jong Hee Chae, Jieun Choi, Ki Joong Kim

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Il Han YooDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-7438-6925
Woojoong KimPediatric Clinical Neuroscience Center, Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-0539-1448
Jaeso ChoDepartment of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0002-2479-3856
Hunmin KimDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea. 5714@snubh.org.ORCID https://orcid.org/0000-0001-6689-3495
Byung Chan LimPediatric Clinical Neuroscience Center, Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-8509-4135
Hee HwangDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-7964-1630
Jong Hee ChaePediatric Clinical Neuroscience Center, Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9162-0138
Jieun ChoiDepartment of Pediatrics, SMG-SNU Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-6845-8745
Ki Joong KimPediatric Clinical Neuroscience Center, Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-0849-125X
Seoul National University Children's Hospital · KRSeoul National University Bundang Hospital · KRSeoul National University · KRSNUH SMG-SNU Boramae Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTo identify whether serum uric acid levels are significantly higher in patients with benign convulsion associated with mild gastroenteritis (CwG) than in patients with acute gastroenteritis.

methodsThis retrospective study compared the serum levels of uric acid between CwG, acute gastroenteritis, and febrile seizure after correcting for the varying degree of mild dehydration using serum HCO₃- levels. We also compared the serum uric acid levels between patients with CwG and febrile seizures in order to exclude the effect of seizures on uric acid.

resultsThis study included 154 CwG patients (age range 0.73-3.19 years), 2,938 patients with acute gastroenteritis, and 154 patients with febrile seizure. The serum uric acid level was significantly higher in CwG patients than in patients with acute gastroenteritis [9.79±2.16 mg/dL vs. 6.04±2.3 mg/dL (mean±SD),

conclusionsWe have confirmed that serum uric acid is elevated in CwG patients even after correcting for their dehydration status, and that this was not a postictal phenomenon. Highly elevated serum uric acid in CwG could be a useful clinical indicator of CwG in patients with acute gastroenteritis.

Indexed as

gastroenteritisseizureuric acid

Identifiers

PMID31591838
PMCPMC6785459
OpenAlexW2971712134

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.